Clinical applications of artificial intelligence: Living evidence

Living evidence tables provide high level summaries of key studies and evidence on a particular topic, and links to sources. They are reviewed regularly and updated as new evidence and information is published.

This page is part of the Artificial Intelligence series.

This table describes areas where artificial intelligence is being used for direct clinical care. This includes examples of established tools, pilot studies, or research projects near the stage of being ready for implementation trials.

To develop this living table:

  • Systematic reviews on artificial intelligence published from 2021 to May 2023 were screened in PubMed.
  • Since May 2023, a weekly PubMed search on artificial intelligence has been conducted to continually update the table.
  • Articles are screened for those that describe established uses of AI in clinical care, pilot studies of implementation, or large research studies and/or systematic reviews which identify areas where AI has positive benefits and is close to implementation / trial stage.
  • Grey literature sources are identified via Google or through publications and websites of well-known organisations with relevance to the Australian clinical context (e.g. World Health Organization, OECD, NICE, The King’s Fund, US Centers for Disease Control and Prevention, etc).
  • Initiatives involving robots or robotic surgery without any other AI integrated, are excluded.

Content is grouped by patient journey stage.

Regular checks are conducted for new content and any updates are highlighted.

On this page:

Diagnosis and prognosis

AI applicationScientific evidence Actual use in healthcare systems

Clinical risk prediction models

Tools that predict health outcomes either at present (diagnostic) or in the future (prognostic).1

These are mainly produced in the academic context and face several barriers to clinical implementation. Therefore, there are few examples currently rolled out.2

Emerging positive evidence. These have been used for:

Diagnostic tools

Oncology

  • deep learning, and in particular convolutional neural network models, to diagnose breast, lung, liver, brain and cervical cancer3
  • predicting epidermal growth factor receptor mutation status in non-small cell lung cancer4
  • deep learning models of multi-omics data for lung cancer prediction5
  • AI driven data analysis to identify ovarian cancer6
  • predicting lymph node   metastasis in early-stage colorectal cancers, potentially refining clinical   decisions and improving outcomes7
  • AI assisted polyp   detection used via colonoscopy for improving accuracy of colorectal cancer   diagnosis 8
  • various forms of AI to diagnose and classify leukaemia quickly9, 10
  • AI, particularly machine learning for pancreatic cancer risk prediction11
  • AI-driven liver cancer diagnosis, including biomarker and image analysis12 and prediction of recurrence13
  • ultrasound-based radiomics as a novel approach to predicting breast cancer markers14
  • CT, MRI and PET-CT-based radiomics as a novel approach to detecting genetic mutation status in patients with lung cancer15
  • AI use in radiotherapy to improve prediction accuracy, dose calculation, treatment design and dose delivery16
  • machine learning applied to cytopathological data for diagnosing solid tumours17

Cardiovascular

  • diagnosis, classification, and treatment of cardiovascular disease18
  • AI models for high accuracy diagnosis of cardiovascular disorders including reduced ejection fraction, valvular heart disease and cardiomyopathes19
  • machine learning algorithms to identify patients at high risk of left ventricular hypertrophy. This could reduce unnecessary next step MRI tests20
  • use of AI in cardiac intensive care to analyse patient data to make prompt and accurate clinical decisions21
  • identification of hypertension and assessment of its secondary effects22
  • cardiac diagnostic accuracy, particularly in cardiac imaging and electrocardiogram analysis23
  • deep learning techniques to automate transthoracic echocardiogram analysis and support clinical judgments24
  • deep learning to advance diagnostic accuracy and personalised care in heart failure management25
  • AI-based methods for detecting left ventricular hypertrophy26
  • AI-enabled ECG for accurate risk prediction of short and long-term mortality from future cardiovascular events27

Acute illness

  • multiple types of AI, but most commonly artificial neural networks, to diagnose and prognosticate acute appendicitis28
  • machine learning techniques for pulmonary embolism diagnosis and risk prediction29
  • predicting community-acquired pneumonia-related hospitalisation risks, complications, and mortality30
  • detecting new-onset atrial fibrillation in ICU-treated patients31
  • AI/machine learning to detect and identify patients at high risk of UTIs32

Neurology/Psychology

  • AI analysis of CT images to improve efficiencies in the diagnosis of stroke 33
  • machine learning analysis of a wide range of different data for the detection and diagnosis of cognitive impairment in Parkinson’s Disease34
  • machine learning to improve the accuracy and efficiency of epilepsy diagnosis35 and seizure characterisation36
  • machine learning to assist in diagnosis of attention deficit hyperactivity disorder37
  • AI to predict adverse events in patients deteriorating in psychiatric settings38

Other

  • discriminant analysis and artificial neural network predictive models which have demonstrated strong ability to differentiate between glaucoma patients and controls39
  • increasing the efficiency of diagnosis in neuro-ophthalmology40
  • AI-assisted total body positron emission tomography to facilitate rapid imaging, low-dose imaging protocols, improved diagnostic capabilities and higher patient comfort41
  • various AI models which can predict falls risk with a high level of accuracy42
  • deep learning models which are highly accurate in the detection of voice pathology, including laryngoscopy images acoustic input43
  • deep learning algorithms to detect mucosal healing in ulcerative colitis44
  • deep learning for obesity diagnosis and prediction45
  • AI-assisted imaging demonstrates high diagnostic efficacy for developmental dysplasia of the hip46

Predicting disease progression

Acute care

  • AI assessment tools to guide timely treatment and resuscitation services for people injured in disasters47
  • machine learning algorithms that predict clinical deterioration in hospitalised adult patients48
  • AI triage systems used to classify triage levels and predict mortality and ICU admission49
  • deep learning-based frameworks have high accuracy for  automated lung CT segmentation and predicting acute respiratory distress syndrome50
  • machine learning for prediction of neonatal sepsis51
  • machine learning to differentiate between Kawasaki disease and other febrile illnesses52
  • machine learning for predicting mortality in adult critically ill patients with sepsis53

Neurology

  • machine learning algorithms to predict future epilepsy in people at risk54
  • large language models can extract more predictive information from clinical notes than can be collected from traditional statistical modelling, for predicting likelihood of a single epileptic event becoming recurrent55
  • estimating the course and progression of Alzheimer’s disease at the early stages, which has treatment implications56
  • machine learning algorithms have increasing accuracy at predicting delayed cerebral ischaemia57
  • deep learning combined with imaging and molecular analysis enables more accurate prognostication of patients with gliomas58
  • machine and deep learning improve spinal cord injury management by predicting quality of life, functional and neurological outcomes and estimating occurrence of adverse events59, 60
  • AI, in particular convolutional neural networks, are highly accurate at diagnosing dementia and Alzheimer’s, however, it has been noted that almost all studies in the field rely on one particular dataset61, 62

Oncology

  • machine learning models have demonstrated considerable potential in predicting post-treatment survival and disease progression in head and neck cancer63
  • early prediction of radiation pneumonitis in lung cancer patients using machine learning64
  • AI has high sensitivity and specificity in automating the assessment of HER2 immunohistochemistry for breast cancer diagnosis65
  • AI is promising for automating the assessment of HER2 immunohistochemistry for breast cancer diagnosis65

Chronic illness progression and survival

  • machine learning algorithms to predict individualised risk and time to diabetic retinopathy progression over 5 years, potentially allowing personalised screening intervals66
  • deep neural network analysis of the posterior tibial artery waveform can provide independent prediction of death, major adverse cardiac events, and major adverse limb events in patients evaluated for peripheral artery disease67
  • machine learning algorithms have supported the update of a risk stratification tool for acute coronary syndrome, which predicts mortality and adverse outcomes68
  • machine learning algorithms to predict kidney disease progression69

Infectious diseases

  • machine learning is a viable approach for developing non-time-based predictions for HIV deaths70

Prognostic factors

  • machine learning to identify time to surgery as the most important variable associated with colon cancer survival71
  • deep learning to stratify patients with colorectal cancer into risk groups and survival outcomes72
  • deep learning analysis of ECG data to identify patients at high risk of diabetes type 273
  • The CHA(2)DS(2)-VASc score is used to predict the risk of stroke in patients with atrial fibrillation.74 It is the gold-standard risk prediction model for atrial fibrillation management as recommended by the National Institute of Health and Care Excellence.
  • Machine learning has been used to analyse survey data from the ‘45 and up study’,75 to assess the risk of Australians developing cardiovascular disease.
  • In Westmead   Hospital’s emergency department, the Sepsis Risk Tool Dashboard combines a   patient’s age, gender and vitals and calculates a sepsis risk percentage for   each patient to support the clinician in assessing if sepsis is a risk or   not. It ensures that patients who are waiting for care are not missed or   deteriorate.76

Early detection of illness via real-time data analysis

 
  • eHealth have a   current project detecting sepsis in Emergency waiting rooms from patients’   vital signs.77
  • Multi-lingual   AI in Western Sydney LHD has been used to diagnose long COVID via self-report   questionnaires conducted over the phone.78

Image analysis

  • Software typically   uses deep learning AI, particularly deep learning, to assist with radiology   and pathology processes.79
  • Automated whole slide   imaging (WSI) scanners are able to render high-resolution images of entire   glass slides and combine these images with innovative digital pathology tools   to make it possible to integrate imaging into all aspects of pathology   reporting including anatomical, clinical, and molecular pathology.80

Consistent positive evidence foridentifying and interpreting mammographic regions suspicious for cancer,81-88

  • including when predicting survival outcomes87
  • particularly positive results when AI assist with double screening84
  • improved cancer detection rates with improved workflows and reduced recall rates89
  • results have included generalisability across datasets from multiple countries.84

Emerging positive evidence onimproved diagnosis and/or prognosis for:

Abdominal / Gastrointestinal

  • a number of common liver diseases including focal liver lesions and fatty liver90-92
  • AI based pathology tool for scoring metabolic dysfunction associated with steatohepatitis93
  • detection of adenomas and polyps in colonoscopy to facilitate earlier diagnosis of colorectal neoplasia and cancer94-100
  • AI-assisted colonoscopy to automatically detect and characterise endoscopic lesions or abnormalities and facilitate IBD management101-103
  • AI-assisted identification of patients with rectal cancer who could achieve pathological complete response following neoadjuvant chemoradiotherapy104, 105
  • AI-assisted detection, classification, and segmentation of pancreatic lesions106
  • detection of early-stage oesophageal squamous cell carcinoma via computer-aided detection systems107
  • detection of dysmotility within the oesophagus using oesophageal physiologic testing108
  • AI analysis of hepatocellular carcinoma digital slides, including for diagnosis109 and to serve as a biomarker for progression-free survival in patients treated with atezolizumab–bevacizumab110
  • detection and differentiation of pancreatic cancer lesion subtypes111
  • detection of pancreatic space-occupying lesion via AI-assisted endoscopic ultrasound112
  • kidney transplant biopsy analysis and digital pathology to identify appropriate donor organs and early signs of organ rejection113
  • identification of patterns in complex histopathology data from renal biopsy114
  • urolithiasis diagnosis, monitoring and treatment using AI modalities115
  • abdominal organ lesions due to improved image quality available via deep learning image reconstruction116
  • the   VisioCyt® test using deep learning automated image processing for urothelial   bladder cancers has improved sensitivity, but lower specificity compared to   standard cytology117
  • identification of lymph node metastasis in patients   with pancreatic ductal adenocarcinoma via CT-based radiomics algorithms and   deep learning models118
  • automated detection of urinary stones from   non-contrast computed tomography119

Pulmonary/Chest

  • screening of COVID-19 pneumonia on chest CT, compared to radiologists120
  • ultrasound imaging for predicting lymph node metastasis in breast cancer patients121
  • breast cancer diagnosis using deep learning and multimodal ultrasound122
  • lung lesions on chest x-ray, compared to non-radiologist physicians123
  • lung cancer screening, especially in enhancing nodule detection sensitivity, reducing false-positive rates, and classifying nodules124
  • pulmonary embolism detection on computed tomography   pulmonary angiogram125
  • diagnosis of pneumothorax via deep learning   (requires training with local data)126
  • identifying phenotypes and risk categories in   patients with normal results on myocardial perfusion imaging127
  • AI-based screening of cardiac amyloidosis-suggestive   uptake in patients undergoing scintigraphy128
  • AI-enhanced electrocardiography for accurate   diagnosis and management of cardiovascular diseases129
  • diagnosis of different degrees of coronary artery   stenosis via deep learning based on coronary angiography or coronary CT   angiography images130
  • diagnosis and management of chronic obstructive   pulmonary disease via machine and deep learning131
  • diagnosis of cardiac amyloidosis via AI-enhanced ECG   models132
  • myocarditis diagnosis, prognosis and better understanding   of molecular dynamics using AI applications133
  • aortic stenosis diagnosis using deep learning   approaches134

Head and neck

  • machine learning for the analysis and evaluation of   various hair and skin assessments135
  • artificial intelligence for analysis of ultrasound images   to diagnose malignant thyroid nodules, particularly when compared to   radiologists and surgeons with less experience136, 137
  • segmenting, detecting, and classifying head and neck   cancers via deep learning138
  • meningioma classification, grading, outcome   prediction, and segmentation via deep or machine learning139
  • differentiating thyroid nodules and accurately forecasting   lymph node metastasis via deep learning140, 141
  • intracranial haemorrhage assessed via non-contrast CT scans142
  • intracranial aneurysms, including accurate detection and improved clinician sensitivity and reading times143-145
  • temporomandibular joint diagnosed via AI-analysed cone-beam computed tomography, which eliminates the subjectivity associated with clinician-led diagnosis146
  • caries lesions as diagnosed via various neural networks147
  • classification of glioblastomas from primary CNS lymphomas via MRI-based machine or deep learning techniques148
  • deep learning models for the detection and classification of seizure semiology via video analysis149
  • radiographic estimation of the jaw bone for age and sex can be for use in medico legal scenarios and disaster victim identification150
  • differential diagnosis of neuromyelitis optica spectrum disorder and multiple sclerosis via AI analysis of MRI images151
  • classification of brain tumours via machine learning152, 153
  • diagnosis of Moyamoya disease via deep learning algorithms154
  • classification and segmentation of oral squamous cell carcinoma via deep learning155

Ocular156

  • sight-threatening eye diseases, via retinal image analysis, as well as prediction of complex systemic disorders such as heart failure and myocardial infarction157
  • classification of distinct multiple sclerosis subtypes based on retinal features, aiding in disease characterisation and guiding tailored therapeutic strategies158
  • keratoconus diagnosis supported by AI triaging tools159
  • Al diagnostic systems that screen for diabetic retinopathy have been shown to have good accuracy,160 save clinicians in real-world settings significant amounts of time161 as well as being cost-saving in both Indigenous and non-Indigenous populations in Australia162
  • AI detection of diabetic macular oedema163
  • detection of pathological myopia from colour fundus images164
  • screening and early diagnosis of the main causes of blindness via smartphone technology (such as cataract, glaucoma, diabetic retinopathy, and age-related macular degeneration)165
  • deep learning algorithms for detecting angle closure in patients with glaucoma166
  • AI screening tool for detecting retinopathy of prematurity167

Radiology and medical imaging

  • MRI data analysis allowing for more accurate tumour   characterisation and small tumour segmentation168
  • identifying benign and soft tissue tumours via   radiomics and deep learning169
  • detecting and segmenting brain metastases via MRI   image analysis by deep learning170
  • MRI diagnosis of ACL or knee meniscus tears via deep   learning171, 172
  • AI for bone fracture detection – where AI can be of   great value in cases where radiologists are not available but isn’t as   accurate as radiologists at present173
  • AI-detected scaphoid and distal radius fractures174
  • generative AI models produce reports of similar clinical accuracy and textual quality to radiologist reports while providing higher textual quality than teleradiologist reports. Implementation of these models could enable timely alerts to life-threatening pathology while aiding imaging interpretation and documentation175
  • fracture diagnosis using AI and human assessment showed higher diagnostic accuracy in wrist and ankle fractures when compared with spine and rib fractures176

Other

  • AI in theranostics to analyse personalised patient risk classification, provide prognostic forecasts, or personalised dosimetry177
  • AI assistance in detecting and grading prostate   cancer, predicting patient outcomes, and identifying molecular subtypes 178-181
  • AI supported tumour origin differentiation using   cytological histology182
  • deep learning supported diagnosis of osteoporosis183, 184
  • artificial intelligence algorithms in osteoarthritis   detection185
  • detection and classification of skin cancer via deep   and machine learning, either independently or for double screening186-189
  • diagnosis of lymphoma by AI (deep learning and   machine learning)190
  • rheumatology MRI analysis to address diagnostic   support, disease classification, activity assessment and progression   monitoring191
  • AI-based video monitoring systems offer improved   efficiency and objectivity in the screening, diagnosis and treatment of   movement disorders192, 193
  • gait analysis for diagnosis of Parkinson’s Disease   via deep learning194

Mixed evidence on the effectiveness ofimage analysisas used for diagnosis, for example:

  • of basal cell carcinoma by non-invasive diagnostic modalities via handcrafted radiomics and deep-learning models195
  • diagnosis and management of pigmented skin lesions via  mobile phone-powered AI technology.196
  • NICE has recommended   the use of AI contouring technologies to speed up treatment planning for   those undergoing external beam radiotherapy for cancers.197
  • Automated whole slide   imaging (WSI) scanners are now approved for use in primary diagnosis by the   FDA.80
  • BreastScreen NSW has   an AI evaluation and clinical integration project underway to compare deep   machine learning AI technology for detecting cancers in screening mammograms,   to usual practice with radiologists only.198
  • RPA Virtual hospital   is piloting a wound care app which stores photos of patients’ wounds at   different timepoints in the cloud. It uses image recognition technology to   accurately measure the wound's dimensions, perimeters, and surface area and   analyses the tissue composition of the wound over time as healing takes   place.199

Curative care

AI application Scientific evidence Actual use in healthcare systems

Clinical prediction models

Tools that predict health outcomes either in the future, depending on a variety of patient and treatment parameters.1

Emerging positive evidence.These have been used for:

  • predicting treatment success, such as
    • which patients with COVID-19 would benefit from cortico-therapy to avoid pulmonary fibrosis.200 Results were collated into a visual decision-making tree for easy clinical use
    • appropriate treatment and disease management strategies in kidney disease69
    • pre-operative risk stratification via ECGdem for high-risk surgical candidates, to inform individualised treatment strategies201
    • tracking and predicting responses to medical and surgical treatments in epilepsy54
    • which patients with prostate cancer may be eligible for clinical trials or have faster progressing cancers202
    • using radiomics to assess the tumour microenvironment, in order to monitoring breast cancer treatments203
    • identifying new categories for treatment outcomes across large cohorts, to better understand responses to methotrexate in juvenile idiopathic arthritis204
    • predicting drug resistance and patient prognosis in pulmonary tuberculosis205
    • enhancing personalised treatments and advancing precision oncology via deep learning in cancer genomics and histopathology206
    • using causal machine learning to predict drug treatment outcomes including efficacy and toxicity207
    • stereotactic radiosurgery outcomes in patients with brain metastasis208
    • using machine learning in melanoma immunotherapy response and prognosis209
    • AI processing of omics data through protein and gene pattern classification to tailor breast cancer treatment210
    • using machine learning to predict post-operative outcomes for patients undergoing gastrointestinal surgery211
  • predicting severity in order to inform treatment options:
    • predicting the severity of postoperative scars to aid clinicians in scar management treatment decisions.212
  • A machine learning-powered cardiovascular disease risk tool, developed by Apollo Hospitals in India, has proven more accurate than conventional risk stratification approaches commonly used in Europe and India.213 The tool is now being used in at least eight countries and has been adapted for other non-communicable diseases, such as diabetes, asthma and liver fibrosis.213
  • A US hospital uses a model to predict which patients are at highest risk of metastatic disease, to inform their cancer treatment approach.214

AI powered image analysis

Can be used for planning treatment.

Emerging positive evidence. These have been used for:

  • acute medical monitoring
    • monitoring and treatment of acute and hard-to-heal wounds and burns215
  • surgical planning, such as
    • deep learning for lung tumour segmentation accuracy216
    • machine learning to improve neuroanatomic localisation and lateralisation in epilepsy54
    • automatic assessment of aortic root morphology for transcatheter aortic valve implantation planning.217
  • OSAIRIS,   the first cloud-based open-source AI imaging software is already saving   radiologists around two hours per patient at Cambridge University Hospitals.   The machine learning based tool is used for the three dimensional   segmentation of normal tissue from cancerous tissue during radiotherapy   planning for patients with head and neck cancer or prostate cancer.218

AI driven surgical monitoring and decision making

Emerging positive evidence for:

  • assisting in surgical decision-making in real time219
    • random forest driven surgical decision-making for total knee arthroplasty220
    • neural network driven rapid nanopore sequencing to enable molecular subclassification of central nervous system tumours221
  • monitoring patient vitals during surgery
    • the hypotension prediction index can predict intra-operative hypotensive episodes in real time with high accuracy and hence reduce the duration of hypotension222
 

AI assisted antimicrobial treatment decisions

Emerging positive evidence. This has been used for:

  • improving the rate of appropriate empirical antibiotic treatment while reducing antibiotic costs and the use of broad-spectrum antibiotic treatment223
  • supporting clinical decisions by accurately predicting antimicrobial resistance in critical pathogens224

Supportive care

AI application Scientific evidence Actual use in healthcare systems

Chatbots - a computer program designed to have a text-based ‘conversation’ with a patient.

Emerging positive evidence when used for:

  • promoting healthy lifestyles
    • increasing physical activity, fruit and vegetable consumption, sleep duration and sleep quality  across a range of populations and age groups, for both short- and longer-term interventions.225
    • promoting healthy lifestyles, smoking cessation, treatment/medication adherence and reducing substance abuse226
  • self-management of mental health conditions227
  • self-management of insulin dosing in type 2 diabetes228

Mixed evidence on effectiveness when used for

  • chronic disease management
    • some apps and wearables are designed to communicate only to the patient, while others also send data back to managing health teams229
    • users find chatbots acceptable and easy to use, but there remains a lack of reliable and comparable evidence on their efficacy227, 229-231
  • supporting physical activity goals226, 232

Limited but negative evidence when usedfor:

  • weight loss and healthy diet support232
  • A multilingual chatbot in Victoria provided support and information on COVID-19. It responded to user queries and links to further information and support services, and is currently being expanded to provide support on broader issues.233
  • MyEleanor, an AI-powered conversational platform, has been used to remind patients in the US of appointments, medication schedules, check in on their health and flag them for clinician follow-up as needed. It was built on thousands of hours of real phone conversations between patients, nurses, and occupational therapists and leverages multiple Machine learning models including Large Language models.234
  • A US hospital is designing ‘virtual nurses’ for chronic care that use an automated ‘voice’ to speak to, patients. They are designed to remind patients to take medication, follow through with care plans, schedule appointments, review medication issues and help patients navigate care-access issues.214

Clinical prediction models for supportive patient care and managing chronic conditions.

Emerging positive evidence when used for early identification of at-risk patients.For example:

  • predicting the risks of complications
    • in cardiovascular disease, prediction models have identified the important roles of sex and social determinants of health in outcome predictions235
    • in heart failure, natural language processing of clinical documentation can improve analysis of disease progression and response to treatment236
    • in diabetes care, prediction models can contribute to better quality of care, better autonomy of patients and reduction of complications, costs of medical care and mortality.237
  • predicting risk of readmission
    • AI models can predict older patients at high risk for readmission as well as provide recommendations for transitional care management to effectively reduce readmission rates238
    • integrating electronic medical record datasets and machine learning algorithms to predict 30 day heart failure readmission239
  • predicting individualised medication responses
    • in hypertension care, machine learning can support individualised recommendations for drug choices and dosages to achieve certain blood pressure targets.240
 

AI-interpreted remote patient monitoring.

Limited but emerging positive evidence.This technology can be used for patients at home or for continuous monitoring of inpatients:241

  • AI support for chronic disease management
    • AI-assisted insulin management for type 1 and 2 diabetes242
    • AI-supported non-invasive blood glucose monitoring243

  • identification of patient health status
    • identification of patients affected by cardiovascular disease, via smartwatches244
    • identification of acceptable ECG data via ‘smartvests’ that monitor vital signs244
  • alerting health services to patient status and risk
    • abnormal heartbeats are identified via a portable ECG device which then alerts clinicians244
    • inpatient remote patient monitoring can free up clinician time and reduce workload by removing the need for frequent in person observation checks.245
  • Nepean   Blue Mountains LHD are trialling the use of a telehealth lab to remote   monitor patient vital signs. It currently calculates heartrate from facial   analysis.246

AI-delivered self-guided interventions

Limited but emerging positive evidence. AI can deliver standardised interventions directly to patients without the need for direct clinician involvement.

  • for patient-guided,   online mental health interventions where AI-delivered care can enhance   treatment effectiveness and adherence.247

·

Notes

^ denotes grey literature, conference proceeding or pre-peer review source.

References

  1. Binuya MAE, Engelhardt EG, Schats W, et al. Methodological guidance for the evaluation and updating of clinical prediction models: a systematic review. BMC Medical Research Methodology. 2022 2022/12/12;22(1):316. DOI: 10.1186/s12874-022-01801-8
  2. Sharma V, Davies A, Ainsworth J. Clinical risk prediction models: the canary in the coalmine for artificial intelligence in healthcare? BMJ Health & Care Informatics. 2021;28(1):e100421. DOI: 10.1136/bmjhci-2021-100421
  3. Tandon R, Agrawal S, Rathore NPS, et al. A systematic review on deep learning-based automated cancer diagnosis models. Journal of Cellular and Molecular Medicine. 2024 2024/03/01;28(6):e18144. DOI: https://doi.org/10.1111/jcmm.18144
  4. Nguyen HS, Ho DKN, Nguyen NN, et al. Predicting EGFR Mutation Status in Non-Small Cell Lung Cancer Using Artificial Intelligence: A Systematic Review and Meta-Analysis. Acad Radiol. 2024 Feb;31(2):660-83. DOI: 10.1016/j.acra.2023.03.040
  5. Tran T-O, Vo TH, Le NQK. Omics-based deep learning approaches for lung cancer decision-making and therapeutics development. Briefings in Functional Genomics. 2024;23(3):181-92. DOI: 10.1093/bfgp/elad031
  6. The Lancet Digital H. Digital transformation of ovarian cancer diagnosis and care. The Lancet Digital Health. 2024 2024/03/01/;6(3):e145. DOI: https://doi.org/10.1016/S2589-7500(24)00027-X
  7. Thompson N, Morley-Bunker A, McLauchlan J, et al. Use of artificial intelligence for the prediction of lymph node metastases in early-stage colorectal cancer: systematic review. BJS Open. 2024;8(2):zrae033. DOI: 10.1093/bjsopen/zrae033
  8. Park DK, Kim EJ, Im JP, et al. A prospective multicenter randomized controlled trial on artificial intelligence assisted colonoscopy for enhanced polyp detection. Scientific Reports. 2024 2024/10/26;14(1):25453. DOI: 10.1038/s41598-024-77079-1
  9. Patel H, Shah H, Patel G, et al. Hematologic cancer diagnosis and classification using machine and deep learning: State-of-the-art techniques and emerging research directives. Artificial Intelligence in Medicine. 2024 2024/06/01/;152:102883. DOI: https://doi.org/10.1016/j.artmed.2024.102883
  10. Ram M, Afrash MR, Moulaei K, et al. Application of artificial intelligence in chronic myeloid leukemia (CML) disease prediction and management: a scoping review. BMC Cancer. 2024 2024/08/20;24(1):1026. DOI: 10.1186/s12885-024-12764-y
  11. Mishra AK, Chong B, Arunachalam SP, et al. Machine Learning Models for Pancreatic Cancer Risk Prediction Using Electronic Health Record Data—A Systematic Review and Assessment. Official journal of the American College of Gastroenterology | ACG. 2024;119(8).
  12. Calderaro J, Žigutytė L, Truhn D, et al. Artificial intelligence in liver cancer — new tools for research and patient management. Nature Reviews Gastroenterology & Hepatology. 2024 2024/08/01;21(8):585-99. DOI: 10.1038/s41575-024-00919-y
  13. Wu L, Lai Q, Li S, et al. Artificial intelligence in predicting recurrence after first-line treatment of liver cancer: a systematic review and meta-analysis. BMC Medical Imaging. 2024 2024/10/07;24(1):263. DOI: 10.1186/s12880-024-01440-z
  14. Fu Y, Zhou J, Li J. Diagnostic performance of ultrasound-based artificial intelligence for predicting key molecular markers in breast cancer: A systematic review and meta-analysis. PLOS ONE. 2024;19(5):e0303669. DOI: 10.1371/journal.pone.0303669
  15. Chen J, Chen A, Yang S, et al. Accuracy of machine learning in preoperative identification of genetic mutation status in lung cancer: A systematic review and <em>meta</em>-analysis. Radiotherapy and Oncology. 2024;196. DOI: 10.1016/j.radonc.2024.110325
  16. Zadnorouzi M, Abtahi SMM. Artificial intelligence (AI) applications in improvement of IMRT and VMAT radiotherapy treatment planning processes: A systematic review. Radiography. 2024;30(6):1530-5. DOI: 10.1016/j.radi.2024.09.049
  17. Hays P. Artificial intelligence in cytopathological applications for cancer: a review of accuracy and analytic validity. European Journal of Medical Research. 2024 2024/11/19;29(1):553. DOI: 10.1186/s40001-024-02138-2
  18. Armoundas AA, Narayan SM, Arnett DK, et al. Use of Artificial Intelligence in Improving Outcomes in Heart Disease: A Scientific Statement From the American Heart Association. Circulation. 2024 2024/04/02;149(14):e1028-e50. DOI: 10.1161/CIR.0000000000001201
  19. Elias P, Jain SS, Poterucha T, et al. Artificial Intelligence for Cardiovascular Care—Part 1: Advances: JACC Review Topic of the Week. Journal of the American College of Cardiology. 2024 2024/06/18/;83(24):2472-86. DOI: https://doi.org/10.1016/j.jacc.2024.03.400
  20. Naderi H, Ramírez J, van Duijvenboden S, et al. Predicting left ventricular hypertrophy from the 12-lead electrocardiogram in the UK Biobank imaging study using machine learning. European Heart Journal - Digital Health. 2023;4(4):316-24. DOI: 10.1093/ehjdh/ztad037
  21. Huerta N, Rao SJ, Isath A, et al. The premise, promise, and perils of artificial intelligence in critical care cardiology. Progress in Cardiovascular Diseases. 2024 2024/09/01/;86:2-12. DOI: https://doi.org/10.1016/j.pcad.2024.06.006
  22. Gudigar A, Kadri NA, Raghavendra U, et al. Automatic identification of hypertension and assessment of its secondary effects using artificial intelligence: A systematic review (2013–2023). Computers in Biology and Medicine. 2024 2024/04/01/;172:108207. DOI: https://doi.org/10.1016/j.compbiomed.2024.108207
  23. Sutanto H. Transforming clinical cardiology through neural networks and deep learning: A guide for clinicians. Current Problems in Cardiology. 2024 2024/04/01/;49(4):102454. DOI: https://doi.org/10.1016/j.cpcardiol.2024.102454
  24. G S, Gopalakrishnan U, Parthinarupothi RK, et al. Deep learning supported echocardiogram analysis: A comprehensive review. Artificial Intelligence in Medicine. 2024 2024/05/01/;151:102866. DOI: https://doi.org/10.1016/j.artmed.2024.102866
  25. Petmezas G, Papageorgiou VE, Vassilikos V, et al. Recent advancements and applications of deep learning in heart failure: Α systematic review. Computers in Biology and Medicine. 2024 2024/06/01/;176:108557. DOI: https://doi.org/10.1016/j.compbiomed.2024.108557
  26. Siranart N, Deepan N, Techasatian W, et al. Diagnostic accuracy of artificial intelligence in detecting left ventricular hypertrophy by electrocardiograph: a systematic review and meta-analysis. Scientific Reports. 2024 2024/07/10;14(1):15882. DOI: 10.1038/s41598-024-66247-y
  27. Sau A, Pastika L, Sieliwonczyk E, et al. Artificial intelligence-enabled electrocardiogram for mortality and cardiovascular risk estimation: a model development and validation study. The Lancet Digital Health. 2024;6(11):e791-e802. DOI: 10.1016/S2589-7500(24)00172-9
  28. Issaiy M, Zarei D, Saghazadeh A. Artificial Intelligence and Acute Appendicitis: A Systematic Review of Diagnostic and Prognostic Models. World Journal of Emergency Surgery. 2023 2023/12/19;18(1):59. DOI: 10.1186/s13017-023-00527-2
  29. Puchades R, Tung-Chen Y, Salgueiro G, et al. Artificial intelligence for predicting pulmonary embolism: A review of machine learning approaches and performance evaluation. Thrombosis Research. 2024;234:9-11. DOI: 10.1016/j.thromres.2023.12.002
  30. Barbieri MA, Battini V, Sessa M. Artificial intelligence for the optimal management of community-acquired pneumonia. Current Opinion in Pulmonary Medicine. 2024;30(3).
  31. Glaser K, Marino L, Stubnya JD, et al. Machine learning in the prediction and detection of new-onset atrial fibrillation in ICU: a systematic review. Journal of Anesthesia. 2024 2024/06/01;38(3):301-8. DOI: 10.1007/s00540-024-03316-6
  32. Shen L, An J, Wang N, et al. Artificial intelligence and machine learning applications in urinary tract infections identification and prediction: a systematic review and meta-analysis. World Journal of Urology. 2024 2024/08/01;42(1):464. DOI: 10.1007/s00345-024-05145-4
  33. Technologies CJoH. RapidAI for Stroke Detection and AI Implementation Review. Canada2024 [cited 29 Nov 2024]. Available from: https://www.canjhealthtechnol.ca/index.php/cjht/article/view/OP0556
  34. Altham C, Zhang H, Pereira E. Machine learning for the detection and diagnosis of cognitive impairment in Parkinson’s Disease: A systematic review. PLOS ONE. 2024;19(5):e0303644. DOI: 10.1371/journal.pone.0303644
  35. Han K, Liu C, Friedman D. Artificial intelligence/machine learning for epilepsy and seizure diagnosis. Epilepsy & Behavior. 2024;155. DOI: 10.1016/j.yebeh.2024.109736
  36. Lucas A, Revell A, Davis KA. Artificial intelligence in epilepsy — applications and pathways to the clinic. Nature Reviews Neurology. 2024 2024/06/01;20(6):319-36. DOI: 10.1038/s41582-024-00965-9
  37. Caselles-Pina L, Quesada-López A, Sújar A, et al. A systematic review on the application of machine learning models in psychometric questionnaires for the diagnosis of attention deficit hyperactivity disorder. European Journal of Neuroscience. 2024 2024/08/01;60(3):4115-27. DOI: https://doi.org/10.1111/ejn.16288
  38. Velasquez VT, Chang J, Waddell A. The development of early warning scores or alerting systems for the prediction of adverse events in psychiatric patients: a scoping review. BMC Psychiatry. 2024 2024/10/28;24(1):742. DOI: 10.1186/s12888-024-06052-z
  39. Pucchio A, Krance S, Pur DR, et al. The role of artificial intelligence in analysis of biofluid markers for diagnosis and management of glaucoma: A systematic review. Eur J Ophthalmol. 2023 Sep;33(5):1816-33. DOI: 10.1177/11206721221140948
  40. Lapka M, Straňák Z. The Current State of Artificial Intelligence in Neuro-Ophthalmology. A Review. Cesk Slov Oftalmol. 2023 Winter;3(Ahead of Print):1001-12. DOI: 10.31348/2023/33
  41. Shiyam Sundar LK, Gutschmayer S, Maenle M, et al. Extracting value from total-body PET/CT image data - the emerging role of artificial intelligence. Cancer Imaging. 2024 2024/04/11;24(1):51. DOI: 10.1186/s40644-024-00684-w
  42. González-Castro A, Leirós-Rodríguez R, Prada-García C, et al. The Applications of Artificial Intelligence for Assessing Fall Risk: Systematic Review. J Med Internet Res. 2024;26:e54934. DOI: 10.2196/54934
  43. Barlow J, Sragi Z, Rivera-Rivera G, et al. The Use of Deep Learning Software in the Detection of Voice Disorders: A Systematic Review. Otolaryngology–Head and Neck Surgery. 2024 2024/06/01;170(6):1531-43. DOI: https://doi.org/10.1002/ohn.636
  44. Rimondi A, Gottlieb K, Despott EJ, et al. Can artificial intelligence replace endoscopists when assessing mucosal healing in ulcerative colitis? A systematic review and diagnostic test accuracy meta-analysis. Digestive and Liver Disease. 2024;56(7):1164-72. DOI: 10.1016/j.dld.2023.11.005
  45. Yi X, He Y, Gao S, et al. A review of the application of deep learning in obesity: From early prediction aid to advanced management assistance. Diabetes & Metabolic Syndrome: Clinical Research & Reviews. 2024 2024/04/01/;18(4):103000. DOI: https://doi.org/10.1016/j.dsx.2024.103000
  46. Chen M, Cai R, Zhang A, et al. The diagnostic value of artificial intelligence-assisted imaging for developmental dysplasia of the hip: a systematic review and meta-analysis. Journal of Orthopaedic Surgery and Research. 2024 2024/08/29;19(1):522. DOI: 10.1186/s13018-024-05003-4
  47. Tahernejad A, Sahebi A, Abadi ASS, et al. Application of artificial intelligence in triage in emergencies and disasters: a systematic review. BMC Public Health. 2024 2024/11/18;24(1):3203. DOI: 10.1186/s12889-024-20447-3
  48. van der Vegt AH, Campbell V, Mitchell I, et al. Systematic review and longitudinal analysis of implementing Artificial Intelligence to predict clinical deterioration in adult hospitals: what is known and what remains uncertain. Journal of the American Medical Informatics Association. 2024;31(2):509-24. DOI: 10.1093/jamia/ocad220
  49. Porto BM. Improving triage performance in emergency departments using machine learning and natural language processing: a systematic review. BMC Emergency Medicine. 2024 2024/11/18;24(1):219. DOI: 10.1186/s12873-024-01135-2
  50. Zhou Y, Mei S, Wang J, et al. Development and validation of a deep learning-based framework for automated lung CT segmentation and acute respiratory distress syndrome prediction: a multicenter cohort study. eClinicalMedicine. 2024;75. DOI: 10.1016/j.eclinm.2024.102772
  51. Kainth D, Prakash S, Sankar MJ. Diagnostic Performance of Machine Learning-based Models in Neonatal Sepsis: A Systematic Review. The Pediatric Infectious Disease Journal. 2024;43(9).
  52. Nikravangolsefid N, Reddy S, Truong HH, et al. Machine learning for predicting mortality in adult critically ill patients with Sepsis: A systematic review. Journal of Critical Care. 2024 2024/12/01/;84:154889. DOI: https://doi.org/10.1016/j.jcrc.2024.154889
  53. Kerr WT, McFarlane KN. Machine Learning and Artificial Intelligence Applications to Epilepsy: a Review for the Practicing Epileptologist. Current Neurology and Neuroscience Reports. 2023 2023/12/01;23(12):869-79. DOI: 10.1007/s11910-023-01318-7
  54. Beaulieu-Jones BK, Villamar MF, Scordis P, et al. Predicting seizure recurrence after an initial seizure-like episode from routine clinical notes using large language models: a retrospective cohort study. The Lancet Digital Health. 2023;5(12):e882-e94. DOI: 10.1016/S2589-7500(23)00179-6
  55. Yi F, Zhang Y, Yuan J, et al. Identifying underlying patterns in Alzheimer's disease trajectory: a deep learning approach and Mendelian randomization analysis. eClinicalMedicine. 2023;64. DOI: 10.1016/j.eclinm.2023.102247
  56. Santana LS, Diniz JBC, Rabelo NN, et al. Machine Learning Algorithms to Predict Delayed Cerebral Ischemia After Subarachnoid Hemorrhage: A Systematic Review and Meta-analysis. Neurocritical Care. 2024 2024/06/01;40(3):1171-81. DOI: 10.1007/s12028-023-01832-z
  57. Lv Q, Liu Y, Sun Y, et al. Insight into deep learning for glioma IDH medical image analysis: A systematic review. Medicine. 2024;103(7).
  58. Habibi MA, Naseri Alavi SA, Soltani Farsani A, et al. Predicting the Outcome and Survival of Patients with Spinal Cord Injury Using Machine Learning Algorithms: A Systematic Review. World Neurosurgery. 2024 2024/08/01/;188:150-60. DOI: https://doi.org/10.1016/j.wneu.2024.05.103
  59. Han H, Li R, Fu D, et al. Revolutionizing spinal interventions: a systematic review of artificial intelligence technology applications in contemporary surgery. BMC Surgery. 2024 2024/11/05;24(1):345. DOI: 10.1186/s12893-024-02646-2
  60. Kaur A, Mittal M, Bhatti JS, et al. A systematic literature review on the significance of deep learning and machine learning in predicting Alzheimer's disease. Artificial Intelligence in Medicine. 2024 2024/08/01/;154:102928. DOI: https://doi.org/10.1016/j.artmed.2024.102928
  61. Borchert RJ, Azevedo T, Badhwar A, et al. Artificial intelligence for diagnostic and prognostic neuroimaging in dementia: A systematic review. Alzheimer's & Dementia. 2023 2023/12/01;19(12):5885-904. DOI: https://doi.org/10.1002/alz.13412
  62. Moharrami M, Azimian Zavareh P, Watson E, et al. Prognosing post-treatment outcomes of head and neck cancer using structured data and machine learning: A systematic review. PLOS ONE. 2024;19(7):e0307531. DOI: 10.1371/journal.pone.0307531
  63. Chen Z, Yi G, Li X, et al. Predicting radiation pneumonitis in lung cancer using machine learning and multimodal features: a systematic review and meta-analysis of diagnostic accuracy. BMC Cancer. 2024 2024/11/05;24(1):1355. DOI: 10.1186/s12885-024-13098-5
  64. Wu S, Li X, Miao J, et al. Artificial intelligence for assisted HER2 immunohistochemistry evaluation of breast cancer: A systematic review and meta-analysis. Pathology - Research and Practice. 2024 2024/08/01/;260:155472. DOI: https://doi.org/10.1016/j.prp.2024.155472
  65. Dai L, Sheng B, Chen T, et al. A deep learning system for predicting time to progression of diabetic retinopathy. Nature Medicine. 2024 2024/01/04. DOI: 10.1038/s41591-023-02702-z
  66. McBane RD, Murphree DH, Liedl D, et al. Artificial Intelligence of Arterial Doppler Waveforms to Predict Major Adverse Outcomes Among Patients Evaluated for Peripheral Artery Disease. Journal of the American Heart Association. 2024 2024/02/06;13(3):e031880. DOI: 10.1161/JAHA.123.031880
  67. Wenzl FA, Fox KAA, Lüscher TF. Towards personalized cardiovascular care: Global Registry of Acute Coronary Events 3.0 score heralds artificial intelligence era. European Heart Journal. 2023;44(44):4615-6. DOI: 10.1093/eurheartj/ehad597
  68. Lei N, Zhang X, Wei M, et al. Machine learning algorithms’ accuracy in predicting kidney disease progression: a systematic review and meta-analysis. BMC Medical Informatics and Decision Making. 2022 2022/08/01;22(1):205. DOI: 10.1186/s12911-022-01951-1
  69. Li Y, Feng Y, He Q, et al. The predictive accuracy of machine learning for the risk of death in HIV patients: a systematic review and meta-analysis. BMC Infectious Diseases. 2024 2024/05/06;24(1):474. DOI: 10.1186/s12879-024-09368-z
  70. Alaimo L, Moazzam Z, Woldesenbet S, et al. Artificial intelligence to investigate predictors and prognostic impact of time to surgery in colon cancer. Journal of Surgical Oncology. 2023 2023/05/01;127(6):966-74. DOI: https://doi.org/10.1002/jso.27224
  71. Jiang X, Hoffmeister M, Brenner H, et al. End-to-end prognostication in colorectal cancer by deep learning: a retrospective, multicentre study. The Lancet Digital Health. 2024;6(1):e33-e43. DOI: 10.1016/S2589-7500(23)00208-X
  72. Kim J, Yang H-L, Kim SH, et al. Deep learning-based long-term risk evaluation of incident type 2 diabetes using electrocardiogram in a non-diabetic population: a retrospective, multicentre study. eClinicalMedicine. 2024;68. DOI: 10.1016/j.eclinm.2024.102445
  73. Hendry J. eHealth NSW is using AI to detect sepsis in hospital admissions. IT News; 2022 [cited 23 Oct 2023]. Available from: https://www.itnews.com.au/news/ehealth-nsw-is-using-ai-to-detect-sepsis-in-hospital-admissions-580419
  74. John W. Chatbots detect long covid by phone in a world first. Medical Republic; 2023 [cited 23 Oct 2023]. Available from: https://www.medicalrepublic.com.au/chatbots-detect-long-covid-by-phone-in-a-world-first/93428
  75. Rajpurkar P, Lungren MP. The Current and Future State of AI Interpretation of Medical Images. New England Journal of Medicine. 2023 2023/05/25;388(21):1981-90. DOI: 10.1056/NEJMra2301725
  76. Shafi S, Parwani AV. Artificial intelligence in diagnostic pathology. Diagnostic Pathology. 2023 2023/10/03;18(1):109. DOI: 10.1186/s13000-023-01375-z
  77. Lång K, Josefsson V, Larsson A-M, et al. Artificial intelligence-supported screen reading versus standard double reading in the Mammography Screening with Artificial Intelligence trial (MASAI): a clinical safety analysis of a randomised, controlled, non-inferiority, single-blinded, screening accuracy study. The Lancet Oncology. 2023;24(8):936-44. DOI: 10.1016/S1470-2045(23)00298-X
  78. Yoon JH, Strand F, Baltzer PAT, et al. Standalone AI for Breast Cancer Detection at Screening Digital Mammography and Digital Breast Tomosynthesis: A Systematic Review and Meta-Analysis. Radiology. 2023 2023/06/01;307(5):e222639. DOI: 10.1148/radiol.222639
  79. Dembrower K, Crippa A, Colón E, et al. Artificial intelligence for breast cancer detection in screening mammography in Sweden: a prospective, population-based, paired-reader, non-inferiority study. The Lancet Digital Health. DOI: 10.1016/S2589-7500(23)00153-X
  80. McKinney SM, Sieniek M, Godbole V, et al. International evaluation of an AI system for breast cancer screening. Nature. 2020 2020/01/01;577(7788):89-94. DOI: 10.1038/s41586-019-1799-6
  81. Ng AY, Oberije CJG, Ambrózay É, et al. Prospective implementation of AI-assisted screen reading to improve early detection of breast cancer. Nature Medicine. 2023 2023/11/16. DOI: 10.1038/s41591-023-02625-9
  82. Eriksson M, Román M, Gräwingholt A, et al. European validation of an image-derived AI-based short-term risk model for individualized breast cancer screening&#x2014;a nested case-control study. The Lancet Regional Health – Europe. DOI: 10.1016/j.lanepe.2023.100798
  83. Amgad M, Hodge JM, Elsebaie MAT, et al. A population-level digital histologic biomarker for enhanced prognosis of invasive breast cancer. Nature Medicine. 2023 2023/11/27. DOI: 10.1038/s41591-023-02643-7
  84. Schopf CM, Ramwala OA, Lowry KP, et al. Artificial Intelligence-Driven Mammography-Based Future Breast Cancer Risk Prediction: A Systematic Review. Journal of the American College of Radiology. 2024;21(2):319-28. DOI: 10.1016/j.jacr.2023.10.018
  85. Fisches ZV, Ball M, Mukama T, et al. Strategies for integrating artificial intelligence into mammography screening programmes: a retrospective simulation analysis. The Lancet Digital Health. 2024;6(11):e803-e14. DOI: 10.1016/S2589-7500(24)00173-0
  86. Popa SL, Grad S, Chiarioni G, et al. Applications of Artificial Intelligence in the Automatic Diagnosis of Focal Liver Lesions: A Systematic Review. J Gastrointestin Liver Dis. 2023 Apr 1;32(1):77-85. DOI: 10.15403/jgld-4755
  87. Zhao Q, Lan Y, Yin X, et al. Image-based AI diagnostic performance for fatty liver: a systematic review and meta-analysis. BMC Medical Imaging. 2023 2023/12/11;23(1):208. DOI: 10.1186/s12880-023-01172-6
  88. Lu F, Meng Y, Song X, et al. Artificial Intelligence in Liver Diseases: Recent Advances. Advances in Therapy. 2024 2024/03/01;41(3):967-90. DOI: 10.1007/s12325-024-02781-5
  89. Pulaski H, Harrison SA, Mehta SS, et al. Clinical validation of an AI-based pathology tool for scoring of metabolic dysfunction-associated steatohepatitis. Nature Medicine. 2024 2024/11/04. DOI: 10.1038/s41591-024-03301-2
  90. Barua I, Vinsard DG, Jodal HC, et al. Artificial intelligence for polyp detection during colonoscopy: a systematic review and meta-analysis. Endoscopy. 2020 2020/09/29;53(03):277-84. DOI: 10.1055/a-1201-7165
  91. Hassan C, Spadaccini M, Iannone A, et al. Performance of artificial intelligence in colonoscopy for adenoma and polyp detection: a systematic review and meta-analysis. Gastrointestinal Endoscopy. 2021;93(1):77-85.e6. DOI: 10.1016/j.gie.2020.06.059
  92. Lou S, Du F, Song W, et al. Artificial intelligence for colorectal neoplasia detection during colonoscopy: a systematic review and meta-analysis of randomized clinical trials. eClinicalMedicine. 2023;66. DOI: 10.1016/j.eclinm.2023.102341
  93. Mehta A, Kumar H, Yazji K, et al. Effectiveness of artificial intelligence-assisted colonoscopy in early diagnosis of colorectal cancer: a systematic review. International Journal of Surgery. 2023;109(4).
  94. Li J, Lu J, Yan J, et al. Artificial intelligence can increase the detection rate of colorectal polyps and adenomas: a systematic review and meta-analysis. European Journal of Gastroenterology & Hepatology. 2021;33(8).
  95. Zhang H, Yang X, Tao Y, et al. Diagnostic accuracy of endocytoscopy via artificial intelligence in colorectal lesions: A systematic review and meta‑analysis. PLOS ONE. 2023;18(12):e0294930. DOI: 10.1371/journal.pone.0294930
  96. Wei MT, Fay S, Yung D, et al. Artificial Intelligence–Assisted Colonoscopy in Real-World Clinical Practice: A Systematic Review and Meta-Analysis. Clinical and Translational Gastroenterology. 2024;15(3).
  97. Pal P, Pooja K, Nabi Z, et al. Artificial intelligence in endoscopy related to inflammatory bowel disease: A systematic review. Indian Journal of Gastroenterology. 2024 2024/02/01;43(1):172-87. DOI: 10.1007/s12664-024-01531-3
  98. Iacucci M, Santacroce G, Zammarchi I, et al. Artificial intelligence and endo-histo-omics: new dimensions of precision endoscopy and histology in inflammatory bowel disease. The Lancet Gastroenterology & Hepatology. DOI: 10.1016/S2468-1253(24)00053-0
  99. Li N, Yang J, Li X, et al. Accuracy of artificial intelligence-assisted endoscopy in the diagnosis of gastric intestinal metaplasia: A systematic review and meta-analysis. PLOS ONE. 2024;19(5):e0303421. DOI: 10.1371/journal.pone.0303421
  100. Shen H, Jin Z, Chen Q, et al. Image-based artificial intelligence for the prediction of pathological complete response to neoadjuvant chemoradiotherapy in patients with rectal cancer: a systematic review and meta-analysis. Radiol Med. 2024 Apr;129(4):598-614. DOI: 10.1007/s11547-024-01796-w
  101. He J, Wang S-x, Liu P. Machine learning in predicting pathological complete response to neoadjuvant chemoradiotherapy in rectal cancer using MRI: a systematic review and meta-analysis. British Journal of Radiology. 2024;97(1159):1243-54. DOI: 10.1093/bjr/tqae098
  102. Rousta F, Esteki A, shalbaf A, et al. Application of artificial intelligence in pancreas endoscopic ultrasound imaging- A systematic review. Computer Methods and Programs in Biomedicine. 2024 2024/06/01/;250:108205. DOI: https://doi.org/10.1016/j.cmpb.2024.108205
  103. Leggett CL. Endoscopic screening for oesophageal cancer: empowering artificial intelligence with a high-quality examination. The Lancet Gastroenterology & Hepatology. 2023. DOI: 10.1016/S2468-1253(23)00377-1
  104. Fass O, Rogers BD, Gyawali CP. Artificial Intelligence Tools for Improving Manometric Diagnosis of Esophageal Dysmotility. Current Gastroenterology Reports. 2024 2024/04/01;26(4):115-23. DOI: 10.1007/s11894-024-00921-z
  105. Salehi MA, Harandi H, Mohammadi S, et al. Diagnostic Performance of Artificial Intelligence in Detection of Hepatocellular Carcinoma: A Meta-analysis. Journal of Imaging Informatics in Medicine. 2024 2024/08/01;37(4):1297-311. DOI: 10.1007/s10278-024-01058-1
  106. Zeng Q, Klein C, Caruso S, et al. Artificial intelligence-based pathology as a biomarker of sensitivity to atezolizumab&#x2013;bevacizumab in patients with hepatocellular carcinoma: a multicentre retrospective study. The Lancet Oncology. DOI: 10.1016/S1470-2045(23)00468-0
  107. Cao K, Xia Y, Yao J, et al. Large-scale pancreatic cancer detection via non-contrast CT and deep learning. Nature Medicine. 2023 2023/11/20. DOI: 10.1038/s41591-023-02640-w
  108. Dhali A, Kipkorir V, Srichawla BS, et al. Artificial intelligence assisted endoscopic ultrasound for detection of pancreatic space-occupying lesion: a systematic review and meta-analysis. International Journal of Surgery. 2023;109(12).
  109. Girolami I, Pantanowitz L, Marletta S, et al. Artificial intelligence applications for pre-implantation kidney biopsy pathology practice: a systematic review. Journal of Nephrology. 2022 2022/09/01;35(7):1801-8. DOI: 10.1007/s40620-022-01327-8
  110. Cazzaniga G, Rossi M, Eccher A, et al. Time for a full digital approach in nephropathology: a systematic review of current artificial intelligence applications and future directions. Journal of Nephrology. 2023 2023/09/28. DOI: 10.1007/s40620-023-01775-w
  111. Altunhan A, Soyturk S, Guldibi F, et al. Artificial intelligence in urolithiasis: a systematic review of utilization and effectiveness. World Journal of Urology. 2024 2024/10/17;42(1):579. DOI: 10.1007/s00345-024-05268-8
  112. van Stiphout JA, Driessen J, Koetzier LR, et al. The effect of deep learning reconstruction on abdominal CT densitometry and image quality: a systematic review and meta-analysis. European Radiology. 2022 2022/05/01;32(5):2921-9. DOI: 10.1007/s00330-021-08438-z
  113. Lebret T, Paoletti X, Pignot G, et al. Artificial intelligence to improve cytology performance in urothelial carcinoma diagnosis: results from validation phase of the French, multicenter, prospective VISIOCYT1 trial. World Journal of Urology. 2023 2023/09/01;41(9):2381-8. DOI: 10.1007/s00345-023-04519-4
  114. Castellana R, Fanni SC, Roncella C, et al. Radiomics and deep learning models for CT pre-operative lymph node staging in pancreatic ductal adenocarcinoma: A systematic review and <em>meta</em>-analysis. European Journal of Radiology. 2024;176. DOI: 10.1016/j.ejrad.2024.111510
  115. Panthier F, Melchionna A, Crawford-Smith H, et al. Can Artificial Intelligence Accurately Detect Urinary Stones? A Systematic Review. Journal of Endourology. 2024 2024/08/01;38(8):725-40. DOI: 10.1089/end.2023.0717
  116. Chavoshi M, Zamani S, Mirshahvalad SA. Diagnostic performance of deep learning models versus radiologists in COVID-19 pneumonia: A systematic review and meta-analysis. Clinical Imaging. 2024;107. DOI: 10.1016/j.clinimag.2024.110092
  117. Wang M, Liu Z, Ma L. Application of artificial intelligence in ultrasound imaging for predicting lymph node metastasis in breast cancer: A meta-analysis. Clinical Imaging. 2024;106. DOI: 10.1016/j.clinimag.2023.110048
  118. Li H, Zhao J, Jiang Z. Deep learning-based computer-aided detection of ultrasound in breast cancer diagnosis: A systematic review and meta-analysis. Clinical Radiology. 2024;79(11):e1403-e13. DOI: 10.1016/j.crad.2024.08.002
  119. Lee HW, Jin KN, Oh S, et al. Artificial Intelligence Solution for Chest Radiographs in Respiratory Outpatient Clinics: Multicenter Prospective Randomized Clinical Trial. Annals of the American Thoracic Society. 2022 2023/05/01;20(5):660-7. DOI: 10.1513/AnnalsATS.202206-481OC
  120. Quanyang W, Yao H, Sicong W, et al. Artificial intelligence in lung cancer screening: Detection, classification, prediction, and prognosis. Cancer Medicine. 2024 2024/04/01;13(7):e7140. DOI: https://doi.org/10.1002/cam4.7140
  121. Soffer S, Klang E, Shimon O, et al. Deep learning for pulmonary embolism detection on computed tomography pulmonary angiogram: a systematic review and meta-analysis. Scientific Reports. 2021 2021/08/04;11(1):15814. DOI: 10.1038/s41598-021-95249-3
  122. Sugibayashi T, Walston SL, Matsumoto T, et al. Deep learning for pneumothorax diagnosis: a systematic review and meta-analysis. Eur Respir Rev. 2023 Jun 30;32(168). DOI: 10.1183/16000617.0259-2022
  123. Miller RJH, Bednarski BP, Pieszko K, et al. Clinical phenotypes among patients with normal cardiac perfusion using unsupervised learning: a retrospective observational study. eBioMedicine. 2024;99. DOI: 10.1016/j.ebiom.2023.104930
  124. Spielvogel CP, Haberl D, Mascherbauer K, et al. Diagnosis and prognosis of abnormal cardiac scintigraphy uptake suggestive of cardiac amyloidosis using artificial intelligence: a retrospective, international, multicentre, cross-tracer development and validation study. The Lancet Digital Health. 2024;6(4):e251-e60. DOI: 10.1016/S2589-7500(23)00265-0
  125. Muzammil MA, Javid S, Afridi AK, et al. Artificial intelligence-enhanced electrocardiography for accurate diagnosis and management of cardiovascular diseases. Journal of Electrocardiology. 2024 2024/03/01/;83:30-40. DOI: https://doi.org/10.1016/j.jelectrocard.2024.01.006
  126. Tu L, Deng Y, Chen Y, et al. Accuracy of deep learning in the differential diagnosis of coronary artery stenosis: a systematic review and meta-analysis. BMC Med Imaging. 2024 Sep 16;24(1):243. DOI: 10.1186/s12880-024-01403-4
  127. Wu Y, Xia S, Liang Z, et al. Artificial intelligence in COPD CT images: identification, staging, and quantitation. Respiratory Research. 2024 2024/08/22;25(1):319. DOI: 10.1186/s12931-024-02913-z
  128. Khan LA, Shaikh FH, Khan MS, et al. Artificial intelligence-enhanced electrocardiogram for the diagnosis of cardiac amyloidosis: A systemic review and meta-analysis. Current Problems in Cardiology. 2024 2024/12/01/;49(12):102860. DOI: https://doi.org/10.1016/j.cpcardiol.2024.102860
  129. Łajczak PM, Jóźwik K. Artificial intelligence and myocarditis—a systematic review of current applications. Heart Failure Reviews. 2024 2024/11/01;29(6):1217-34. DOI: 10.1007/s10741-024-10431-9
  130. Popat A, Saini B, Patel M, et al. Diagnostic Accuracy of AI Algorithms in Aortic Stenosis Screening: A Systematic Review and Meta-Analysis. Clin Med Res. 2024 Sep;22(3):145-55. DOI: 10.3121/cmr.2024.1934
  131. Shakeel CS, Khan SJ. Machine learning (ML) techniques as effective methods for evaluating hair and skin assessments: A systematic review. Proceedings of the Institution of Mechanical Engineers, Part H: Journal of Engineering in Medicine. 2023 2024/02/01;238(2):132-48. DOI: 10.1177/09544119231216290
  132. Taha A, Saad B, Taha-Mehlitz S, et al. Analysis of artificial intelligence in thyroid diagnostics and surgery: A scoping review. The American Journal of Surgery. 2024;229:57-64. DOI: 10.1016/j.amjsurg.2023.11.019
  133. Sant VR, Radhachandran A, Ivezic V, et al. From Bench-to-Bedside: How Artificial Intelligence is Changing Thyroid Nodule Diagnostics, a Systematic Review. The Journal of Clinical Endocrinology & Metabolism. 2024;109(7):1684-93. DOI: 10.1210/clinem/dgae277
  134. Rokhshad R, Salehi SN, Yavari A, et al. Deep learning for diagnosis of head and neck cancers through radiographic data: a systematic review and meta-analysis. Oral Radiol. 2024 Jan;40(1):1-20. DOI: 10.1007/s11282-023-00715-5
  135. Maniar KM, Lassarén P, Rana A, et al. Traditional Machine Learning Methods versus Deep Learning for Meningioma Classification, Grading, Outcome Prediction, and Segmentation: A Systematic Review and Meta-Analysis. World Neurosurgery. 2023 2023/11/01/;179:e119-e34. DOI: https://doi.org/10.1016/j.wneu.2023.08.023
  136. Xu J, Xu H-L, Cao Y-N, et al. The performance of deep learning on thyroid nodule imaging predicts thyroid cancer: A systematic review and meta-analysis of epidemiological studies with independent external test sets. Diabetes & Metabolic Syndrome: Clinical Research & Reviews. 2023 2023/11/01/;17(11):102891. DOI: https://doi.org/10.1016/j.dsx.2023.102891
  137. Liu F, Han F, Lu L, et al. Meta-analysis of prediction models for predicting lymph node metastasis in thyroid cancer. World Journal of Surgical Oncology. 2024 2024/10/22;22(1):278. DOI: 10.1186/s12957-024-03566-4
  138. Maghami M, Sattari SA, Tahmasbi M, et al. Diagnostic test accuracy of machine learning algorithms for the detection intracranial hemorrhage: a systematic review and meta-analysis study. BioMedical Engineering OnLine. 2023 2023/12/04;22(1):114. DOI: 10.1186/s12938-023-01172-1
  139. Gu F, Wu X, Wu W, et al. Performance of deep learning in the detection of intracranial aneurysm: A systematic review and meta-analysis. European Journal of Radiology. 2022;155. DOI: 10.1016/j.ejrad.2022.110457
  140. Munaib D, Siddharth A, Mariusz G, et al. Detection of cerebral aneurysms using artificial intelligence: a systematic review and meta-analysis. Journal of NeuroInterventional Surgery. 2023;15(3):262. DOI: 10.1136/jnis-2022-019456
  141. Zhou Z, Jin Y, Ye H, et al. Classification, detection, and segmentation performance of image-based AI in intracranial aneurysm: a systematic review. BMC Medical Imaging. 2024 2024/07/02;24(1):164. DOI: 10.1186/s12880-024-01347-9
  142. Talaat WM, Shetty S, Al Bayatti S, et al. An artificial intelligence model for the radiographic diagnosis of osteoarthritis of the temporomandibular joint. Scientific Reports. 2023 2023/09/25;13(1):15972. DOI: 10.1038/s41598-023-43277-6
  143. Albano D, Galiano V, Basile M, et al. Artificial intelligence for radiographic imaging detection of caries lesions: a systematic review. BMC Oral Health. 2024 2024/02/24;24(1):274. DOI: 10.1186/s12903-024-04046-7
  144. Guha A, Halder S, Shinde SH, et al. How does deep learning/machine learning perform in comparison to radiologists in distinguishing glioblastomas (or grade IV astrocytomas) from primary CNS lymphomas?: a meta-analysis and systematic review. Clinical Radiology. 2024;79(6):460-72. DOI: 10.1016/j.crad.2024.03.007
  145. Ahmedt-Aristizabal D, Armin MA, Hayder Z, et al. Deep learning approaches for seizure video analysis: A review. Epilepsy & Behavior. 2024;154. DOI: 10.1016/j.yebeh.2024.109735
  146. Singh S, Singha B, Kumar S. Artificial intelligence in age and sex determination using maxillofacial radiographs: A systematic review. J Forensic Odontostomatol. 2024 Apr 30;42(1):30-7. DOI: 10.5281/zenodo.11088513
  147. Etemadifar M, Norouzi M, Alaei S-A, et al. The diagnostic performance of AI-based algorithms to discriminate between NMOSD and MS using MRI features: A systematic review and meta-analysis. Multiple Sclerosis and Related Disorders. 2024;87. DOI: 10.1016/j.msard.2024.105682
  148. Silva Santana L, Borges Camargo Diniz J, Mothé Glioche Gasparri L, et al. Application of Machine Learning for Classification of Brain Tumors: A Systematic Review and Meta-Analysis. World Neurosurgery. 2024 2024/06/01/;186:204-18.e2. DOI: https://doi.org/10.1016/j.wneu.2024.03.152
  149. Chukwujindu E, Faiz H, Ai-Douri S, et al. Role of artificial intelligence in brain tumour imaging. European Journal of Radiology. 2024;176. DOI: 10.1016/j.ejrad.2024.111509
  150. Santana LS, Leite M, Yoshikawa MH, et al. Evaluation of deep learning algorithms in detecting moyamoya disease: a systematic review and single-arm meta-analysis. Neurosurgical Review. 2024 2024/06/29;47(1):300. DOI: 10.1007/s10143-024-02537-3
  151. Pirayesh Z, Mohammad-Rahimi H, Ghasemi N, et al. Deep Learning-Based Image Classification and Segmentation on Digital Histopathology for Oral Squamous Cell Carcinoma: A Systematic Review and Meta-Analysis. Journal of Oral Pathology & Medicine. 2024;53(9):551-66. DOI: https://doi.org/10.1111/jop.13578
  152. Parmar UP, Surico PL, Singh RB, et al. Artificial Intelligence (AI) for Early Diagnosis of Retinal Diseases. Medicina.
  153. Zhou Y, Chia MA, Wagner SK, et al. A foundation model for generalizable disease detection from retinal images. Nature. 2023 2023/10/01;622(7981):156-63. DOI: 10.1038/s41586-023-06555-x
  154. Farabi Maleki S, Yousefi M, Afshar S, et al. Artificial Intelligence for Multiple Sclerosis Management Using Retinal Images: Pearl, Peaks, and Pitfalls. Seminars in Ophthalmology. 2024 2024/05/18;39(4):271-88. DOI: 10.1080/08820538.2023.2293030
  155. Vandevenne MMS, Favuzza E, Veta M, et al. Artificial intelligence for detecting keratoconus. Cochrane Database of Systematic Reviews. 2023 (11). DOI: 10.1002/14651858.CD014911.pub2
  156. Joseph S, Selvaraj J, Mani I, et al. Diagnostic Accuracy of Artificial Intelligence-Based Automated Diabetic Retinopathy Screening in Real-World Settings: A Systematic Review and Meta-Analysis. American Journal of Ophthalmology. 2024;263:214-30. DOI: 10.1016/j.ajo.2024.02.012
  157. Abramoff MD, Whitestone N, Patnaik JL, et al. Autonomous artificial intelligence increases real-world specialist clinic productivity in a cluster-randomized trial. npj Digital Medicine. 2023 2023/10/04;6(1):184. DOI: 10.1038/s41746-023-00931-7
  158. Hu W, Joseph S, Li R, et al. Population impact and cost-effectiveness of artificial intelligence-based diabetic retinopathy screening in people living with diabetes in Australia: a cost effectiveness analysis. eClinicalMedicine. 2024;67. DOI: 10.1016/j.eclinm.2023.102387
  159. Lam C, Wong YL, Tang Z, et al. Performance of Artificial Intelligence in Detecting Diabetic Macular Edema From Fundus Photography and Optical Coherence Tomography Images: A Systematic Review and Meta-analysis. Diabetes Care. 2024;47(2):304-19. DOI: 10.2337/dc23-0993
  160. Prashar J, Tay N. Performance of artificial intelligence for the detection of pathological myopia from colour fundus images: a systematic review and meta-analysis. Eye (Lond). 2024 Feb;38(2):303-14. DOI: 10.1038/s41433-023-02680-z
  161. Vilela MAP, Arrigo A, Parodi MB, et al. Smartphone Eye Examination: Artificial Intelligence and Telemedicine. Telemedicine and e-Health. 2023 2024/02/01;30(2):341-53. DOI: 10.1089/tmj.2023.0041
  162. Olyntho MACJ, Jorge CAC, Castanha EB, et al. Artificial Intelligence in Anterior Chamber Evaluation: A Systematic Review and Meta-Analysis. Journal of Glaucoma. 2024;33(9):658-64. DOI: 10.1097/ijg.0000000000002428
  163. Tsai ASH, Yip M, Song A, et al. Implementation of Artificial Intelligence in Retinopathy of Prematurity Care: Challenges and Opportunities. International Ophthalmology Clinics. 2024;64(4).
  164. Eidex Z, Ding Y, Wang J, et al. Deep learning in MRI-guided radiation therapy: A systematic review. Journal of Applied Clinical Medical Physics. 2024 2024/02/01;25(2):e14155. DOI: https://doi.org/10.1002/acm2.14155
  165. Dai X, Zhao B, Zang J, et al. Diagnostic Performance of Radiomics and Deep Learning to Identify Benign and Malignant Soft Tissue Tumors: A Systematic Review and Meta-analysis. Academic Radiology. 2024;31(10):3956-67. DOI: 10.1016/j.acra.2024.03.033
  166. Wang T-W, Hsu M-S, Lee W-K, et al. Brain metastasis tumor segmentation and detection using deep learning algorithms: A systematic review and meta-analysis. Radiotherapy and Oncology. 2024;190. DOI: 10.1016/j.radonc.2023.110007
  167. Santomartino SM, Kung J, Yi PH. Systematic review of artificial intelligence development and evaluation for MRI diagnosis of knee ligament or meniscus tears. Skeletal Radiol. 2024 Mar;53(3):445-54. DOI: 10.1007/s00256-023-04416-2
  168. Herman H, Jaya Kumar Y, Yong Wee S, et al. A Systematic Review on Deep Learning Model in Computer-aided Diagnosis for Anterior Cruciate Ligament Injury. Current Medical Imaging. 2024;20:1-10. DOI: http://dx.doi.org/10.2174/0115734056295157240418043624
  169. Nowroozi A, Salehi MA, Shobeiri P, et al. Artificial intelligence diagnostic accuracy in fracture detection from plain radiographs and comparing it with clinicians: a systematic review and meta-analysis. Clinical Radiology. 2024;79(8):579-88. DOI: 10.1016/j.crad.2024.04.009
  170. Oeding JF, Kunze KN, Messer CJ, et al. Diagnostic Performance of Artificial Intelligence for Detection of Scaphoid and Distal Radius Fractures: A Systematic Review. Journal of Hand Surgery. 2024;49(5):411-22. DOI: 10.1016/j.jhsa.2024.01.020
  171. Huang J, Neill L, Wittbrodt M, et al. Generative Artificial Intelligence for Chest Radiograph Interpretation in the Emergency Department. JAMA Network Open. 2023;6(10):e2336100-e. DOI: 10.1001/jamanetworkopen.2023.36100
  172. Husarek J, Hess S, Razaeian S, et al. Artificial intelligence in commercial fracture detection products: a systematic review and meta-analysis of diagnostic test accuracy. Scientific Reports. 2024 2024/10/04;14(1):23053. DOI: 10.1038/s41598-024-73058-8
  173. Belge Bilgin G, Bilgin C, Burkett BJ, et al. Theranostics and artificial intelligence: new frontiers in personalized medicine. Theranostics. 2024;14(6):2367-78. DOI: 10.7150/thno.94788
  174. Zhu L, Pan J, Mou W, et al. Harnessing artificial intelligence for prostate cancer management. Cell Reports Medicine. 2024;5(4). DOI: 10.1016/j.xcrm.2024.101506
  175. Riaz IB, Harmon S, Chen Z, et al. Applications of Artificial Intelligence in Prostate Cancer Care: A Path to Enhanced Efficiency and Outcomes. American Society of Clinical Oncology Educational Book. 2024 2024/06/01;44(3):e438516. DOI: 10.1200/EDBK_438516
  176. Marletta S, Eccher A, Martelli FM, et al. Artificial intelligence–based algorithms for the diagnosis of prostate cancer: A systematic review. American Journal of Clinical Pathology. 2024;161(6):526-34. DOI: 10.1093/ajcp/aqad182
  177. Fassia M-K, Balasubramanian A, Woo S, et al. Deep Learning Prostate MRI Segmentation Accuracy and Robustness: A Systematic Review. Radiology: Artificial Intelligence. 2024 2024/07/01;6(4):e230138. DOI: 10.1148/ryai.230138
  178. Tian F, Liu D, Wei N, et al. Prediction of tumor origin in cancers of unknown primary origin with cytology-based deep learning. Nature Medicine. 2024 2024/04/16. DOI: 10.1038/s41591-024-02915-w
  179. He Y, Lin J, Zhu S, et al. Deep learning in the radiologic diagnosis of osteoporosis: a literature review. Journal of International Medical Research. 2024 2024/04/01;52(4):03000605241244754. DOI: 10.1177/03000605241244754
  180. Yamamoto N, Shiroshita A, Kimura R, et al. Diagnostic accuracy of chest X-ray and CT using artificial intelligence for osteoporosis: systematic review and meta-analysis. Journal of Bone and Mineral Metabolism. 2024 2024/09/01;42(5):483-91. DOI: 10.1007/s00774-024-01532-4
  181. Mohammadi S, Salehi MA, Jahanshahi A, et al. Artificial intelligence in osteoarthritis detection: A systematic review and meta-analysis. Osteoarthritis and Cartilage. 2024;32(3):241-53. DOI: 10.1016/j.joca.2023.09.011
  182. Lyakhova UA, Lyakhov PA. Systematic review of approaches to detection and classification of skin cancer using artificial intelligence: Development and prospects. Computers in Biology and Medicine. 2024 2024/08/01/;178:108742. DOI: https://doi.org/10.1016/j.compbiomed.2024.108742
  183. Canning K. AI Can Flag Skin Cancer With Near-Perfect Accuracy. Newark, NJ: Medscape News; 2023 [cited 27 Nov 2023]. Available from: https://www.medscape.com/viewarticle/997581
  184. Ye Z, Zhang D, Zhao Y, et al. Deep learning algorithms for melanoma detection using dermoscopic images: A systematic review and meta-analysis. Artificial Intelligence in Medicine. 2024 2024/09/01/;155:102934. DOI: https://doi.org/10.1016/j.artmed.2024.102934
  185. Mirza FN, Haq Z, Abdi P, et al. Artificial Intelligence for Mohs and Dermatologic Surgery: A Systematic Review and Meta-Analysis. Dermatologic Surgery. 2024;50(9).
  186. Bai A, Si M, Xue P, et al. Artificial intelligence performance in detecting lymphoma from medical imaging: a systematic review and meta-analysis. BMC Med Inform Decis Mak. 2024 Jan 8;24(1):13. DOI: 10.1186/s12911-023-02397-9
  187. Adams LC, Bressem KK, Ziegeler K, et al. Artificial intelligence to analyze magnetic resonance imaging in rheumatology. Joint Bone Spine. 2024 2024/05/01/;91(3):105651. DOI: https://doi.org/10.1016/j.jbspin.2023.105651
  188. Park KW, Mirian MS, McKeown MJ. Artificial intelligence-based video monitoring of movement disorders in the elderly: a review on current and future landscapes. Singapore Medical Journal. 2024;65(3).
  189. Tang W, van Ooijen PMA, Sival DA, et al. Automatic two-dimensional & three-dimensional video analysis with deep learning for movement disorders: A systematic review. Artificial Intelligence in Medicine. 2024 2024/10/01/;156:102952. DOI: https://doi.org/10.1016/j.artmed.2024.102952
  190. Franco A, Russo M, Amboni M, et al. The Role of Deep Learning and Gait Analysis in Parkinson’s Disease: A Systematic Review. Sensors. 2024;24(18):5957.
  191. Widaatalla Y, Wolswijk T, Adan F, et al. The application of artificial intelligence in the detection of basal cell carcinoma: A systematic review. Journal of the European Academy of Dermatology and Venereology. 2023 2023/06/01;37(6):1160-7. DOI: https://doi.org/10.1111/jdv.18963
  192. Menzies SW, Sinz C, Menzies M, et al. Comparison of humans versus mobile phone-powered artificial intelligence for the diagnosis and management of pigmented skin cancer in secondary care: a multicentre, prospective, diagnostic, clinical trial. The Lancet Digital Health. 2023;5(10):e679-e91. DOI: 10.1016/S2589-7500(23)00130-9
  193. National Institute for Health and Care Excellence (NICE). Artificial intelligence technologies to speed up contouring in radiotherapy treatment planning. London: NICE; 2023 [cited 23 Oct 2023]. Available from: https://www.nice.org.uk/news/articles/artificial-intelligence-to-speed-up-contouring-in-radiotherapy-treatment-planning
  194. Warner-Smith M, Ren K, Mistry C, et al. Protocol for evaluating the fitness for purpose of an artificial intelligence product for radiology reporting in the BreastScreen New South Wales breast cancer screening programme. BMJ Open. 2024;14(5):e082350. DOI: 10.1136/bmjopen-2023-082350
  195. Sydney Local Health District (SLHD). District trials wound care app in an Australian first. Sydney: SLHD; 2020 [cited 23 Oct 2023]. Available from: https://www.slhd.nsw.gov.au/sydneyconnect/story-District-trials-wound-care-app-in-an-Australian-first.html
  196. Myska V, Genzor S, Mezina A, et al. Artificial-Intelligence-Driven Algorithms for Predicting Response to Corticosteroid Treatment in Patients with Post-Acute COVID-19. Diagnostics (Basel). 2023 May 16;13(10). DOI: 10.3390/diagnostics13101755
  197. Hong S, Zhao Q. Expanding electrocardiogram abilities for postoperative mortality prediction with deep learning. The Lancet Digital Health. DOI: 10.1016/S2589-7500(23)00230-3
  198. Harris S. AI Advances Individualised Prostate Cancer Treatment. Newark, NJ: Medscape News; 2023 [cited 27 Nov 2023]. Available from: https://www.medscape.co.uk/viewarticle/ai-advance-individualised-prostate-cancer-treatment-2023a1000qaa
  199. Lin G, Wang X, Ye H, et al. Radiomic Models Predict Tumor Microenvironment Using Artificial Intelligence—the Novel Biomarkers in Breast Cancer Immune Microenvironment. Technology in Cancer Research & Treatment. 2023 2023/01/01;22:15330338231218227. DOI: 10.1177/15330338231218227
  200. Shoop-Worrall SJW, Lawson-Tovey S, Wedderburn LR, et al. Towards stratified treatment of JIA: machine learning identifies subtypes in response to methotrexate from four UK cohorts. eBioMedicine. 2024;100. DOI: 10.1016/j.ebiom.2023.104946
  201. Zhang F, Zhang F, Li L, et al. Clinical utilization of artificial intelligence in predicting therapeutic efficacy in pulmonary tuberculosis. Journal of Infection and Public Health. 2024 2024/04/01/;17(4):632-41. DOI: https://doi.org/10.1016/j.jiph.2024.02.012
  202. Unger M, Kather JN. Deep learning in cancer genomics and histopathology. Genome Medicine. 2024 2024/03/27;16(1):44. DOI: 10.1186/s13073-024-01315-6
  203. Feuerriegel S, Frauen D, Melnychuk V, et al. Causal machine learning for predicting treatment outcomes. Nature Medicine. 2024 2024/04/01;30(4):958-68. DOI: 10.1038/s41591-024-02902-1
  204. Habibi MA, Rashidi F, Habibzadeh A, et al. Prediction of the treatment response and local failure of patients with brain metastasis treated with stereotactic radiosurgery using machine learning: A systematic review and meta-analysis. Neurosurgical Review. 2024 2024/04/30;47(1):199. DOI: 10.1007/s10143-024-02391-3
  205. Li J, Dan K, Ai J. Machine learning in the prediction of immunotherapy response and prognosis of melanoma: a systematic review and meta-analysis. Frontiers in Immunology. 2024 2024-May-21;15. DOI: 10.3389/fimmu.2024.1281940
  206. Sohrabei S, Moghaddasi H, Hosseini A, et al. Investigating the effects of artificial intelligence on the personalization of breast cancer management: a systematic study. BMC Cancer. 2024 2024/07/18;24(1):852. DOI: 10.1186/s12885-024-12575-1
  207. Wang J, Tozzi F, Ashraf Ganjouei A, et al. Machine learning improves prediction of postoperative outcomes after gastrointestinal surgery: a systematic review and meta-analysis. Journal of Gastrointestinal Surgery. 2024 2024/06/01/;28(6):956-65. DOI: https://doi.org/10.1016/j.gassur.2024.03.006
  208. Kim J, Oh I, Lee YN, et al. Predicting the severity of postoperative scars using artificial intelligence based on images and clinical data. Scientific Reports. 2023 2023/08/18;13(1):13448. DOI: 10.1038/s41598-023-40395-z
  209. World Economic Forum. Scaling smart solutions with AI in health. Geneva: World Economic Forum; 2023 [cited 17 Jul 2023]. Available from: https://www3.weforum.org/docs/WEF_Scaling_Smart_Solutions_with_AI_in_Health_Unlocking_Impact_on_High_Potential_Use_Cases.pdf
  210. Webster P. Six ways large language models are changing healthcare. Nature Medicine. 2023 2023/11/30. DOI: 10.1038/s41591-023-02700-1
  211. Rippon MG, Fleming L, Chen T, et al. Artificial intelligence in wound care: diagnosis, assessment and treatment of hard-to-heal wounds: a narrative review. Journal of Wound Care. 2024;33(4):229-42. DOI: 10.12968/jowc.2024.33.4.229
  212. Wang T-W, Hong J-S, Huang J-W, et al. Systematic review and meta-analysis of deep learning applications in computed tomography lung cancer segmentation. Radiotherapy and Oncology. 2024 2024/08/01/;197:110344. DOI: https://doi.org/10.1016/j.radonc.2024.110344
  213. Saitta S, Sturla F, Gorla R, et al. A CT-based deep learning system for automatic assessment of aortic root morphology for TAVI planning. Computers in Biology and Medicine. 2023 2023/09/01/;163:107147. DOI: https://doi.org/10.1016/j.compbiomed.2023.107147
  214. Senior K. NHS embraces AI-assisted radiotherapy technology. The Lancet Oncology. 2023;July 20. DOI: 10.1016/S1470-2045(23)00353-4
  215. Varghese C, Harrison EM, O’Grady G, et al. Artificial intelligence in surgery. Nature Medicine. 2024 2024/05/01;30(5):1257-68. DOI: 10.1038/s41591-024-02970-3
  216. Longo UG, De Salvatore S, Valente F, et al. Artificial intelligence in total and unicompartmental knee arthroplasty. BMC Musculoskeletal Disorders. 2024 2024/07/22;25(1):571. DOI: 10.1186/s12891-024-07516-9
  217. Vermeulen C, Pagès-Gallego M, Kester L, et al. Ultra-fast deep-learned CNS tumour classification during surgery. Nature. 2023 2023/10/11. DOI: 10.1038/s41586-023-06615-2
  218. Mohammadi I, Firouzabadi SR, Hosseinpour M, et al. Predictive ability of hypotension prediction index and machine learning methods in intraoperative hypotension: a systematic review and meta-analysis. Journal of Translational Medicine. 2024 2024/08/05;22(1):725. DOI: 10.1186/s12967-024-05481-4
  219. Paul M, Andreassen S, Tacconelli E, et al. Improving empirical antibiotic treatment using TREAT, a computerized decision support system: cluster randomized trial. Journal of Antimicrobial Chemotherapy. 2006;58(6):1238-45. DOI: 10.1093/jac/dkl372
  220. Ardila CM, Yadalam PK, González-Arroyave D. Integrating whole genome sequencing and machine learning for predicting antimicrobial resistance in critical pathogens: a systematic review of antimicrobial susceptibility tests. PeerJ. 2024 2024/10/09;12:e18213. DOI: 10.7717/peerj.18213
  221. Singh B, Olds T, Brinsley J, et al. Systematic review and meta-analysis of the effectiveness of chatbots on lifestyle behaviours. npj Digital Medicine. 2023 2023/06/23;6(1):118. DOI: 10.1038/s41746-023-00856-1
  222. Aggarwal A, Tam CC, Wu D, et al. Artificial Intelligence-Based Chatbots for Promoting Health Behavioral Changes: Systematic Review. J Med Internet Res. 2023 Feb 24;25:e40789. DOI: 10.2196/40789
  223. Griffin AC, Xing Z, Khairat S, et al. Conversational Agents for Chronic Disease Self-Management: A Systematic Review. AMIA Annu Symp Proc. 2020;2020:504-13.
  224. Nayak A, Vakili S, Nayak K, et al. Use of Voice-Based Conversational Artificial Intelligence for Basal Insulin Prescription Management Among Patients With Type 2 Diabetes: A Randomized Clinical Trial. JAMA Network Open. 2023;6(12):e2340232-e. DOI: 10.1001/jamanetworkopen.2023.40232
  225. Asan O, Choi E, Wang X. Artificial Intelligence–Based Consumer Health Informatics Application: Scoping Review. J Med Internet Res. 2023 2023/8/30;25:e47260. DOI: 10.2196/47260
  226. Bin Sawad A, Narayan B, Alnefaie A, et al. A Systematic Review on Healthcare Artificial Intelligent Conversational Agents for Chronic Conditions. Sensors.
  227. Kurniawan MH, Handiyani H, Nuraini T, et al. A systematic review of artificial intelligence-powered (AI-powered) chatbot intervention for managing chronic illness. Annals of Medicine. 2024 2024/12/31;56(1):2302980. DOI: 10.1080/07853890.2024.2302980
  228. Oh YJ, Zhang J, Fang M-L, et al. A systematic review of artificial intelligence chatbots for promoting physical activity, healthy diet, and weight loss. International Journal of Behavioral Nutrition and Physical Activity. 2021 2021/12/11;18(1):160. DOI: 10.1186/s12966-021-01224-6
  229. Tan A. Victorian multilingual chatbot to provide Covid-19 support. London: Computer Weekly; 2022 [cited 23 Oct 2023]. Available from: https://www.computerweekly.com/news/252522985/Victorian-multilingual-chatbot-to-provide-Covid-19-support
  230. Business Wire. Ontrak Health Will Bring MyndYou’s AI-Powered, Active Listening Virtual Care Assistant to Its Behavioral Health Members. Yahoo! Finance; 2023 [cited 23 Oct 2023]. Available from: https://www.businesswire.com/news/home/20230328005387/en/Ontrak-Health-Will-Bring-MyndYou%E2%80%99s-AI-Powered-Active-Listening-Virtual-Care-Assistant-to-Its-Behavioral-Health-Members?utm_campaign=shareaholic&utm_medium=copy_link&utm_source=bookmark
  231. Teshale AB, Htun HL, Vered M, et al. A Systematic Review of Artificial Intelligence Models for Time-to-Event Outcome Applied in Cardiovascular Disease Risk Prediction. Journal of Medical Systems. 2024 2024/07/19;48(1):68. DOI: 10.1007/s10916-024-02087-7
  232. Sun GK, Ambrosy AP. Applying Natural Language Processing to Electronic Health Record Data—From Text to Triage. JAMA Network Open. 2024;7(11):e2443934-e. DOI: 10.1001/jamanetworkopen.2024.43934
  233. Gosak L, Martinović K, Lorber M, et al. Artificial intelligence based prediction models for individuals at risk of multiple diabetic complications: A systematic review of the literature. Journal of Nursing Management. 2022 2022/11/01;30(8):3765-76. DOI: https://doi.org/10.1111/jonm.13894
  234. Brown Z, Bergman D, Holt L, et al. Augmenting a Transitional Care Model With Artificial Intelligence Decreased Readmissions. Journal of the American Medical Directors Association. 2023;24(7):958-63. DOI: 10.1016/j.jamda.2023.03.005
  235. Yu M-Y, Son Y-J. Machine learning–based 30-day readmission prediction models for patients with heart failure: a systematic review. European Journal of Cardiovascular Nursing. 2024;23(7):711-9. DOI: 10.1093/eurjcn/zvae031
  236. Yi J, Wang L, Song J, et al. Development of a machine learning-based model for predicting individual responses to antihypertensive treatments. Nutrition, Metabolism and Cardiovascular Diseases. 2024 2024/07/01/;34(7):1660-9. DOI: https://doi.org/10.1016/j.numecd.2024.02.014
  237. Sujith AVLN, Sajja GS, Mahalakshmi V, et al. Systematic review of smart health monitoring using deep learning and Artificial intelligence. Neuroscience Informatics. 2022 2022/09/01/;2(3):100028. DOI: https://doi.org/10.1016/j.neuri.2021.100028
  238. Eghbali-Zarch M, Masoud S. Application of machine learning in affordable and accessible insulin management for type 1 and 2 diabetes: A comprehensive review. Artificial Intelligence in Medicine. 2024 2024/05/01/;151:102868. DOI: https://doi.org/10.1016/j.artmed.2024.102868
  239. Chan PZ, Jin E, Jansson M, et al. AI-Based Noninvasive Blood Glucose Monitoring: Scoping Review. J Med Internet Res. 2024 2024/11/19;26:e58892. DOI: 10.2196/58892
  240. Shaik T, Tao X, Higgins N, et al. Remote patient monitoring using artificial intelligence: Current state, applications, and challenges. WIREs Data Mining and Knowledge Discovery. 2023 2023/03/01;13(2):e1485. DOI: https://doi.org/10.1002/widm.1485
  241. Capdevila X, Macaire P, Bernard N, et al. Remote transmission monitoring for postoperative perineural analgesia after major orthopedic surgery: A multicenter, randomized, parallel-group, controlled trial. J Clin Anesth. 2022 May;77:110618. DOI: 10.1016/j.jclinane.2021.110618
  242. NSW Government News. Using AI to enhance remote patient care. Sydney: NSW Government; 2022 [cited 23 Oct 2023]. Available from: https://www.nsw.gov.au/health/nbmlhd/news/stories/ai-enhances-remote-patient-care
  243. Gutierrez G, Stephenson C, Eadie J, et al. Examining the role of AI technology in online mental healthcare: opportunities, challenges, and implications, a mixed-methods review. Frontiers in Psychiatry. 2024 2024-May-07;15. DOI: 10.3389/fpsyt.2024.1356773

Living evidence tables include some links to low quality sources and an assessment of the original source has not been undertaken. Sources are monitored regularly but due to rapidly emerging information, tables may not always reflect the most current evidence. The tables are not peer reviewed, and inclusion does not imply official recommendation nor endorsement of NSW Health.

Last updated on 3 Dec 2024

Back to top