Emergency Care Institute Clinical tools

Non-invasive and invasive ventilation

Published: March 2026. Next review: 2031. Printed on 23 Jun 2026.


The first step in any resuscitation is the verification or establishment of a patent and protected airway.

Emergency defibrillation is the sole, occasional exception to this principle. Without adequate oxygenation, all other potentially lifesaving manoeuvres will fail.

Assessment

  • Airway patency
  • Breathing efficacy
  • Need for supplemental oxygen

Management

In clinical practice, timely decision-making regarding non-invasive ventilation (NIV) or intubation is crucial. Opting for a well-organised and prepared approach is generally favoured over dealing with a chaotic and uncontrolled airway situation.

While there is a diverse range of presentations, deciding whether to proceed with intubation, withhold it, or opt for NIV may not always be straightforward.

Use The decision to intubate - UpToDate (NSW Health login required) for guidance.

Each facility, local health district or specialty network should have local procedures on indications and management of NIV.

NIV is an effective and safe means of treatment of ventilatory failure. It allows preservation of cough, physiological air warming and humidification, and normal swallowing, feeding and speech.

NIV may prevent the need for intubation and reduce mortality and length of hospital stay in patients experiencing a chronic obstructive pulmonary disease (COPD) exacerbation.

It is recommended for COPD exacerbations associated with hypercapnic respiratory failure and acidosis (defined as partial pressure of carbon dioxide (PaCO2) above 45mmHg and pH below 7.35) despite optimal therapy (including oxygen therapy titrated to maintain SpO2 between 88 and 92%).

These resources offer guidance on indications, contraindications, assessment set-up and care.

Each facility, local health district or specialty network should have local procedures on indications and management of invasive ventilation.

Key questions to guide the decision to intubate:

  • Is patency or protection of the airway at risk?
  • Is oxygenation or ventilation failing?
  • Is intubation anticipated given the expected clinical course?

The airway management clinical tool provides guidance on adult and paediatric intubation, including checklists.

Further reading: Difficult Airway Society Guidelines

Accessed from the Emergency Care Institute website at https://aci.health.nsw.gov.au/networks/eci/clinical/tools/ventilation

Back to top