Any person, 4 weeks to 15 years, presenting unwell without a clear clinical focus.
This protocol is intended to be used by registered and enrolled nurses within their scope of practice and as outlined in The Use of Emergency Care Assessment and Treatment Protocols (PD2024_011). Sections marked triangle or diamond indicate the need for additional prerequisite education prior to use. Check the medication table for dose adjustments and links to relevant reference texts.
- If signs of serious illness, escalate as per local CERS protocol at any point in assessment.
- Consider alternate protocol based on assessment findings.
History prompts, signs and symptoms
These are not exhaustive lists. Maintain an open mind and be aware of cognitive bias.
History prompts
- Presenting complaint
- Onset of symptoms
- Pain assessment
- Feeding history, pattern and behaviours, e.g. breast, bottle or mixed
- Fluid intake, i.e. mL or % of usual feeds
- Fluid output
- Nausea and/or vomiting
- Urinary and bowel changes
- Pre-hospital treatment
- Past admissions
- Medical and surgical history
- Relevant prenatal complications
- Current medications
- Known allergies
- Immunisation history
- Weight
Signs and symptoms
- Irritable or unsettled
- Lethargic
- Reduced activity
- Weak cry
- Poor or reduced tone
- Respiratory distress
- Pallor
- Jaundice
- Poor oral intake
- Poor urine output
- Joint pain or swelling
- Pain
- Fever
- Rash
Red flags
Recognise: identify indicators of actual or potential clinical severity and risk of deterioration.
Respond: carefully consider alternative ECAT protocol. Escalate as per clinical reasoning and local CERS protocol, and continue treatment.
Historical
- Less than 3 months old
- Immunosuppressed
- Low birth weight and/or prematurity, if relevant
- High level of parental or carer concern
Clinical
- Seizure
- Abnormal posturing
- Decreased conscious state
- Limited response or protest
- Floppy baby or decreased tone
- Lethargy or irritability
- Altered, high pitched or continuous cry
- Bulging fontanelle
- Apnoea
- Severe respiratory distress or grunting
- Bradycardia or hypotension, with weak or absent central or peripheral pulses –pre-terminal signs
- Persistent tachycardia
- Pallor
- Mottled
- Cyanotic
- Bilious or projectile vomiting
- Distended abdomen
- Red currant or bloody stool
- Hypothermia
- Non-blanching rash
- Painful erythematous rash
- Severe unexplained pain
- Unable to mobilise, without cause
Remember child or adolescent at risk: patient or carer concern, suspected non-accidental injury or neglect, multiple comorbidities or unplanned return.
Clinical assessment and specified intervention (A to G)
If the patient has any Yellow or Red Zone observations or additional criteria (as per the relevant NSW Standard Emergency Observation Chart), refer and escalate as per local CERS protocol and continue treatment.
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Position
Assessment | Signs of serious illness | Intervention |
---|---|---|
General appearance/first impressions | Abnormal posturing Lethargy Restlessness Decreased conscious state Irritability Limited response or protest | Apply continuous cardiorespiratory monitoring Obtain bare or accurate (minimal clothing) weight Nurse in an infant warmer if available, age-appropriate |
Airway
Assessment | Signs of serious illness | Intervention |
---|---|---|
Patency of airway | Stridor | Maintain airway patency Consider airway opening manoeuvres and positioning If stridor is present, keep the patient calm |
Breathing
Assessment | Signs of serious illness | Intervention |
---|---|---|
Respiratory rate and work of breathing | Grunting Tachypnoea Increased work of breathing Use of accessory muscles | Minimal handling Apply oxygen to maintain SpO2 over 93% Assist ventilation as clinically indicated Commence CPR if breathing is inadequate (switch to cardiorespiratory arrest protocol) |
Auscultate chest (breath sounds) | Poor or unilateral air entry (AE) | |
Oxygen saturation (SpO2) | Hypoxia |
Circulation
Assessment | Signs of serious illness | Intervention |
---|---|---|
Perfusion (capillary refill, skin warmth and colour) Mucosa and skin turgor | Pallor Mottled skin Cyanosis Jaundice Cool or cold peripheries CRT 3 seconds and over | Assess circulation Consider sepsis (suspected) protocol Bradycardia is a late sign and may indicate cardiorespiratory collapse or raised intracranial pressure Hypotension is a late, pre-terminal sign |
Heart rate | Bradycardia Weak peripheral pulses Persistent tachycardia | |
Blood pressure | Hypotension | |
Cardiac rhythm | Arrhythmia | Check cardiac rhythm and consider 12 lead ECG |
IVC and/or pathology | Insert IV cannula, if trained If unable to obtain IV access, consider intraosseous, if trained | |
Signs of shock: tachycardia and CRT 3 seconds and over and/or abnormal skin perfusion and/or hypotension | If signs of shock present, give sodium chloride 0.9% at 20 mL/kg IV/intraosseous bolus once only, maximum dose 1000 mL |
Disability
Assessment | Signs of serious illness | Intervention |
---|---|---|
AVPU | If AVPU shows reduced level of consciousness, continue to GCS, pupillary response and limb strength | |
GCS, pupillary response and limb strength | Neck stiffness Focal neurological signs or seizures | Obtain baseline and repeat assessment as clinically indicated |
Pain | Pain out of proportion to clinical signs | Assess pain. If indicated, give early analgesia as per analgesia section then resume A to G assessment |
Exposure
Assessment | Signs of serious illness | Intervention |
---|---|---|
Temperature | Hypothermia | Actively warm with blankets or radiant heat For infants use skin-to-skin contact with parents and a warm blanket Use warmed fluids if required |
Head-to-toe inspection, including posterior surfaces | Non-blanching rash Painful erythematous rash Swelling of a joint Bruising and/or unexplained injury | Assess for injury, rash and signs of infection |
Fluids
Assessment | Signs of serious illness | Intervention |
---|---|---|
Hydration status | Poor feeding Reduced urine output | Assess fluids, in and out. Document on fluid balance chart. Include gastrointestinal losses |
Nausea and/or vomiting | Bilious vomiting Projectile vomiting | |
Gastrointestinal | Distended abdomen Absent or infrequent bowel actions Red currant or bloody stool Irreducible inguinal hernia |
Glucose
Assessment | Intervention |
---|---|
BGL |
Measure BGL. See medication table for 40% glucose gel dosing If BGL between 2 mmol/L and 3 mmol/L and NOT symptomatic (Yellow Zone criteria):
If BGL less than 2 mmol/L OR symptomatic (Red Zone criteria) OR unable to tolerate oral glucose:
Once stabilised, give patient long-acting carbohydrate and continue to check BGL hourly, or as clinically indicated If BGL over 10 mmol/L:
|
Repeat and document assessment and observations to monitor responses to interventions, identify developing trends and clinical deterioration. Escalate care as required according to the local CERS protocol.
Focused assessment
Complete a secondary survey.
No specific focused assessment. Use clinical judgement and A to G assessment to determine focused assessment.
Precautions and notes
- Signs of serious illness are often difficult to recognise in children. Complete a structured assessment and consider parental or carer concerns.
- Ongoing tachycardia and respiratory distress, despite analgesia, is a concern for serious illness.
Interventions and diagnostics
Specific treatment
- Consider switching to another protocol following initial A to G assessment.
Analgesia
If pain score 1–6 (mild–moderate):
Give paracetamol 15 mg/kg orally once only, maximum dose 1000 mg
and/or ibuprofen, if 3 months and over, 10 mg/kg orally once only, maximum dose 400 mg
If severe pain present, give analgesia and escalate as per local CERS protocol.
Consider non-pharmacological pain relief (appendix).
Procedural analgesia
For pain relief required during procedures only, not used to replace appropriate analgesia.
Sucrose 24%
- 1–18 months: give 1–2 mL orally per procedure
- Maximum dose:
- 1–3 months: up to 5 mL in 24 hours
- 3–18 months: up to 10 mL in 24 hours.
Repeat as needed up to the maximum dose.
Radiology
Radiology will depend on the working diagnosis. It needs to be requested by a medical or nurse practitioner. If there is concern for urgent radiology, escalate as per local CERS protocol.
Pathology
- FBC, UEC, CRP/procalcitonin, VBG with lactate
- Urinalysis:
- Patient who can void in the toilet: mid-stream urine
- Patient who is not toilet trained: clean catch or catheter urine
- Send for MC&S based on clinical presentation. Keep the sample refrigerated if transport is delayed.
- Refer to urine sampling appendix for further detail
- Seriously unwell: coags, blood cultures
- Consider for specific fever sources: wound swab, sputum culture, stool culture and respiratory viral screen
Medications
The patient’s weight is mandatory for calculating fluid and medication doses.
The Broselow Tape or APLS weight table (appendix) can be used only in circumstances where the patient cannot be weighed.
The shaded sections in this protocol are only to be used by registered nurses who have completed the required education.
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Drug | Dose | Route | Frequency |
---|---|---|---|
Up to 25 kg: 25 kg and over: | IM | Once only | |
2 mL/kg | Slow IV injection | Once only | |
Glucose 40% gel | 4 weeks–1 year: 1–5 years: 5 g 6–11 years: 10 g 12 years and over : 15 g | Buccal | Repeat after 15 minutes if required |
Ibuprofen H, R | 3 months and over: Maximum dose 400 mg | Oral | Pain score 1–10 Once only |
0.25–15 L/min, device dependent | Inhalation | Continuous | |
15 mg/kg Maximum dose 1000 mg | Oral | Pain score 1–10 Once only | |
20 mL/kg Maximum dose 1000 mL | IV/intraosseous | Bolus Once only | |
1–18 months: Maximum dose 3–18 months: | Oral | Used during procedures only Repeat if required to maximum dose |
Medications with contraindications or requiring dose adjustment are marked:
- H for patients with known hepatic impairment
- R for patients with known renal impairment.
Escalate to medical or nurse practitioner.
References
- Pocket Book of Hospital Care for Children: Guidelines for the Management of Common Childhood Illnesses. 2nd edition. Geneva: World Health Organization; 2013. 3, Problems of the neonate and young infant. Available from: https://www.ncbi.nlm.nih.gov/books/NBK154443/.
- Clinical Excellence Commission. Between the Flags. Australia: NSW Health; 2021 [cited 23 Feb 2023]. Available from: https://www.cec.health.nsw.gov.au/keep-patients-safe/between-the-flags
- MIMS Australia. Clinical Resources. Australia: MIMS Australia Pty Ltd; 2022 [cited 2 Feb 2023]. Available from: https://www.mimsonline.com.au.acs.hcn.com.au/Search/Search.aspx
- NSW Health. Rural Paediatric Emergency Clinical Guidelines - Third Edition. Australia: NSW Government 2021 [cited 23 Feb 2023]. Available from: https://www1.health.nsw.gov.au/pds/Pages/doc.aspx?dn=GL2021_011
- NSW Health. Australian Medicines Handbook. Australia: Australian Government, NSW; 2022 [cited 23 Feb 2023]. Available from: https://amhonline.amh.net.au.acs.hcn.com.au/
- NSW Health. Australian Medicines Handbook Children’s Dosing Companion Australia: Australian Government, NSW; 2023 [cited 28 Feb 2023]. Available from: https://childrens.amh.net.au.acs.hcn.com.au/?acc=36422
- The Royal Children's Hospital Melbourne. Recognition of the seriously unwell neonate and young infant. Australia: Victoria Health 2019 [cited 10 March 2023]. Available from: https://www.rch.org.au/clinicalguide/guideline_index/Recognition_of_the_seriously_unwell_neonate_and_young_infant/
- The Sydney Children's Hospital Network. Signs of serious illness in children. Australia: NSW Health; 2024 [cited 22 May 2024]. Available from: https://www.schn.health.nsw.gov.au/signs-serious-illness-children-factsheet
Evidence informed |
Information was drawn from evidence-based guidelines and a review of latest available research. For more information, see the development process. |
Collaboration |
This protocol was developed by the ECAT Working Group, led by the Agency for Clinical Innovation. The group involved expert medical, nursing and allied health representatives from local health districts across NSW. Consensus was reached on all recommendations included within this protocol. |
Currency | Due for review: Jan 2026. Based on a regular review cycle. |
Feedback | Email ACI-ECIs@health.nsw.gov.au |
Accessed from the Emergency Care Institute website at https://aci.health.nsw.gov.au/ecat/paediatric/recognition-seriously-unwell-child