Fibrinogen administration in prehospital trauma

This report considers if Fibrinogen Concentrate (FC) is a reasonable alternative to allogeneic products in the prehospital setting by examining the literature regarding patient mortality, intensive care unit (ICU) length of stay, safety, need for additional blood products, storage, administration and costs.

Key points from the report:

Current published evidence is low quality
Suggests FC in hospital setting is safe and effective
Logistic advantages for FC with storage, preparation and more rapid administration

Outcome:

In the absence of allogenic products, FC could be considered as a reasonable prehospital alternative. This is best conducted under clinical trial conditions.